Registration Dossier
Registration Dossier
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EC number: 700-541-9 | CAS number: 1472634-24-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19 JAN 2016 - 09 JUN 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- Commission Regulation (EC) No 440/2008, Annex, Part A
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- 1998
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Water solubility:
- 151 mg/L
- Temp.:
- 30 °C
- pH:
- 5
- Conclusions:
- The solubility of the test item was determined to be 151 mg/L.
- Executive summary:
The water solubility of the test item was tested according to EU Method A.6, OECD Guideline 105 and EPA OPPTS 830.7840 (Water Solubility) in a GLP study at 30 °C. The water solubility at this temperature is 151 mg/L.
Reference
Result of the Main Test:
The results in pure water differed 9 % in a random fashion. The second experiment performed at half the flow rate differed 11 % in a random fashion. The standard deviation between both experiments was determined to be 19 %. Therefore the study is considered to be valid.
Description of key information
The water solubility of the test item was tested according to EU Method A.6, OECD Guideline 105 and EPA OPPTS 830.7840 (Water Solubility) in a GLP study at 30 °C. The water solubility at this temperature is 151 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 151 mg/L
- at the temperature of:
- 30 °C
Additional information
The results in pure water differed 9 % in a random fashion. The second experiment performed at half the flow rate differed 11 % in a random fashion. The standard deviation between both experiments was determined to be 19 %. Therefore the study is considered to be valid.
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