Registration Dossier
Registration Dossier
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EC number: 239-996-9 | CAS number: 15872-89-6
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Diheptyl succinate
- EC Number:
- 239-996-9
- EC Name:
- Diheptyl succinate
- Cas Number:
- 15872-89-6
- Molecular formula:
- C18H34O4
- IUPAC Name:
- 1,4-diheptyl butanedioate
- Test material form:
- liquid
- Details on test material:
- Sample Date: 07/24/2012
LOT: BG9309
Flash Point, ³C, Open cup 198
Specific Grav.@25³C/25³C 0.9337
Constituent 1
Study design
- Analytical monitoring:
- yes
- Details on sampling:
- sterile aqueous buffer solutions of different pH values 4, 7, and 9
- Buffers:
- sterile aqueous buffer solutions of different pH values 4, 7, and 9
- Details on test conditions:
- incubation in dark under lab controlled conditions (constant temperature)
Duration of testopen allclose all
- Duration:
- 5 d
- pH:
- 4
- Temp.:
- 25 °C
- Initial conc. measured:
- 1 g/L
- Duration:
- 5 d
- pH:
- 7
- Temp.:
- 25 °C
- Initial conc. measured:
- 1 g/L
- Duration:
- 5 d
- pH:
- 9
- Temp.:
- 25 °C
- Initial conc. measured:
- 1 g/L
Results and discussion
- Preliminary study:
- since half-life was less than 10% for preliminary studies conducted at 50C, it is concluded the given material is hydrolitically stable at pH 4,7, and 9
- Transformation products:
- not measured
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 4
- Temp.:
- 50 °C
- Remarks on result:
- hydrolytically stable based on preliminary test
- pH:
- 7
- Temp.:
- 50 °C
- Remarks on result:
- hydrolytically stable based on preliminary test
- pH:
- 9
- Temp.:
- 50 °C
- Remarks on result:
- hydrolytically stable based on preliminary test
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- hydrolitically stable at pH 4, 7, and 9
- Executive summary:
hydrolitically stable at pH 4, 7, and 9 using OECD 111
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