Sodium 4-[(C16-18-(even numbered)-alkylamino)carbonyl]benzoate

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

05 September 2017 - 01 November 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

GLP compliance:

yes (incl. QA statement)

Type of method:

capillary method

Remarks:

and differential scanning calorimetry

Specific details on test material used for the study:

- Appearance/physical state: White solid
- Batch: A026/99 and A026/50-01
- Purity: 100% (UVCB)
- Expiry date: 01 July 2019
- Storage conditions: Room temperature, in the dark

Key result

Decomposition:

yes

Remarks:

The test item was determined to visually decompose, without melting, from approximately 200°C (473 K). Therefore, due to decomposition, the melting point / melting range of the test item could not be determined.

Decomp. temp.:

200 °C

Overall result: The test item was determined to visually decompose, without melting, from approximately 200°C (473 K).

Observation	°C	K
The test item was observed as being a white powder at the start of the evaluation.	25	298
The test item remained unchanged in appearance.	151	424
The test item became wet-looking in appearance.	153	426
The test item was shrinking.	156	429
The test item was a slightly wet-looking, white solid.	166	439
The test item began discoloring to off-white in coloration.	200	473
The test item continued to discolor as heating continued, becoming brown/amber in appearance.	202	475
The whole sample of test item was now an amber colored solid.	206	479
The test item continued to darken in color further.	210	483
On completion of the determination, the test item was a dark amber/brown solid.	200	493
On removal of the capillary tube from the metal block apparatus, the test item residue was a brown solid, which remained as discrete particles, which were not adhered together.	-	-

Conclusions:

The test item was determined to visually decompose, without melting, from approximately 200°C (473 K).

Executive summary:

The melting point of Sodium 4-[(C16-18-(even numbered)-alkylamino)carbonyl]benzoate, could not be determined in a GLP-compliant capillary test following OECD guideline 102 (Envigo 2018) due to decomposition. The study is considered relevant and reliable for use for this endpoint.

Description of key information

The test item was determined to visually decompose, without melting, from approximately 200°C (473 K).

Additional information

The melting point of Sodium 4-[(C16-18-(even numbered)-alkylamino)carbonyl]benzoate, could not be determined in a GLP-compliant capillary test following OECD guideline 102 (Envigo 2018) due to decomposition. The study is considered relevant and reliable for use for this endpoint.