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EC number: 928-348-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Oxidising properties
Administrative data
Link to relevant study record(s)
- Endpoint:
- oxidising liquids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07.January.2008-04.March.2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study, guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.21 (Oxidising Properties (Liquids))
- Deviations:
- no
- Principles of method if other than guideline:
- Test objective
The objective of the test is to determine the oxidizing properties of a liquid test item.
Principle
The test item is mixed in a 1 to 1 ratio by weight with dried fibrous cellulose and introduced into a pressure vessel. If during mixing or filling spontaneous ignition occurs no further testing is necessary and the test item will be considered as an oxidizer. If no spontaneous ignition occurs, the mixture is heated in a pressure vessel and the mean time taken for the pressure to rise from 690 to 2070 kPa above atmospheric pressure
is determined. This is compared with the mean pressure rise time for a 1 to 1 mixture of the 66% w/w aqueous nitric acid solution and dried fibrous cellulose. - GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- TEST ITEM
Identification LCE07102
Identification of the flask LCE07102, Req Nr: 24/07/00262/05,
Net: 2,500 L
Batch LCE07102
Expiry date Not provided
Supplier SEPPIC
Appearance Yellow liquid
Packaging 2 White opaque plastic flasks
Quantity received 2 x 1 Kg
Date of the reception December 12, 2007
Storage In darkness at room temperature
Identification number for the study 07-157
REFERENCE ITEM
Oxidizing properties liquids (A21)
Identification Nitric acid 66%
Supplier ACROS
Reference 124660010
Batch A0198010001
Expiry date of the reference item October 17, 2010
Periodicity of validation During each test
Results See the test for details
Conformity Yes - Contact with:
- powdered cellulose
- Duration of test (contact time):
- ca. 3 d
- Key result
- Sample tested:
- reference mixture with 65% nitric acid + cellulose (1:1 ratio)
- Parameter:
- mean pressure rise time
- Result:
- 4 505 ms
- Key result
- Sample tested:
- test mixture as specified
- Parameter:
- mean pressure rise time
- Result:
- 33 147 ms
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The mean pressure rise time obtained with the mixture reference item / cellulose was: 4505 ms.
The mean pressure rise time obtained with the mixture test item / cellulose was: 33147 ms.
The mean pressure rise time obtained with the mixture test item / cellulose was higher than the mean pressure rise time obtained with the mixture reference item.
The test item was not considered to have oxidizing properties in our experimental conditions. - Executive summary:
OXIDIZING PROPERTIES
In compliance with Commission Directive 2004/73/EEC
A21 method (2004)
AMENDMENTS
No amendment was requested.
DEVIATIONS
No incident which could have affected the quality or the interpretation of the results obtained was observed.
RESULTS
The mean pressure rise time obtained with the mixture reference item / cellulose was: 4505 ms.
The mean pressure rise time obtained with the mixture test item / cellulose was: 33147 ms.
The mean pressure rise time obtained with the mixture test item / cellulose was higher than the mean pressure rise time obtained with the mixture reference item.
The test item was not considered to have oxidizing properties in our experimental conditions.
- Endpoint:
- oxidising liquids
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- REPORTING FORMAT FOR THE CATEGORY APPROACH
Registered substance (as identified in Section 1.1 identification) has similar chemical structure as the others members of the Category "Amino Acid Alkyl Amides, Sodium or
Potassium Salts" (the source chemicals).
The category “Amino Acid Alkyl Amides, Sodium or Potassium Salts” has been developed and evaluated to cover the assessment of the intrinsic properties of several similar
substances within the context of REACH Regulation. The Category includes sodium or potassium salts of amino acid alkyl amides, with a carbon chain length range of C6-C16 and an
aminoacidic pool of not selected aminoacids reflecting the natural distributions of aminoacids in various vegetables and cereals.
1. HYPOTHESIS FOR THE CATEGORY APPROACH (ENDPOINT LEVEL)
The Category has been built up considering the common chemical structure of its members. They are UVCB substances and they share the following features:
- they are salts of amino acid alkyl amides
- they are sodium or potassium salts
- the carbon chain length ranges between C6 and C16
- the carbon chain derives from cocoyl or lauroyl fatty acids
- the aminoacidic part of the molecules comes from a pool of aminoacids
- the aminoacids pool reflects the natural distributions of aminoacids in various vegetables and cereals.
Overall, the Category was formed on the hypothesis that substances sharing this common chemical structure can be considered analogues and can share intrinsic properties too. No
trends in properties is expected, except for those physicochemical properties depending on the carbon chain length.
2. CATEGORY APPROACH JUSTIFICATION
These substances share (i) eye damage and (ii) the absence of significant systemic toxicity. - Key result
- Sample tested:
- other: read-across approach
- Remarks:
- read-across approach
- Parameter:
- other: read-across approach
- Remarks on result:
- other: No oxidizing properties.
- Remarks:
- The registered substance is not considered to have oxidizing properties.
- Conclusions:
- Find below the oxidising properties result obtained for one similar substance (a comparable value is expected):
- The test item [similar substance 2] was not considered to have oxidizing properties in our experimental conditions.
The weight of evidence can be applied as the substances are very similar.
The registered substance is not considered to have oxidizing properties. - Executive summary:
The category “Amino Acid Alkyl Amides, Sodium or Potassium Salts” was formed on the hypothesis that substances sharing common chemical structure can be considered analogues and can share intrinsic properties too.
Based on this assumption, this property may be assessed using available data for the category members.
The category has been assessed for members characterized by:
- sodium or potassium salts
- the carbon chain length ranges between C6 and C16
- the aminoacids pool reflects the natural distributions of aminoacids in various vegetables and cereals.
Referenceopen allclose all
Mixture test item /cellulose
Assay number | Reference item mass (g) | Cellulose mass (g) | Atmospheric pressure (kPa) | Corrected pressure rise time (ms) | Mean corrected pressure rise time (ms) | Theoritical calculated min and max accepted value: +/- 30% of the mean pressure rise time (ms) |
2 | 2.4933 | 2.5002 | 98.4 | 35164 | 33147 | [23203 ; 43091] |
3 | 2.4947 | 2.5041 | 98.6 | 41923 | 33147 | [23203 ; 43091] |
4 | 2.4924 | 2.5020 | 98.6 | 38428 | 33147 | [23203 ; 43091] |
10 | 2.5000 | 2.5026 | 98.8 | 25692 | 33147 | [23203 ; 43091] |
11 | 2.5126 | 2.5052 | 98.9 | 24526 | 33147 | [23203 ; 43091] |
Mixture reference item/cellulose
ber | Reference item mass (g) | Cellulose mass (g) | Atmospheric pressure (kPa) | Corrected pressure rise time (ms) | Mean corrected pressure rise time (ms) | Theoritical calculated min and max accepted value: +/- 30% of the mean pressure rise time (ms) |
1 | 2.4998 | 2.5042 | 98.3 | 4630 | 4505 | [3153 ; 5857] |
2 | 2.5073 | 2.5028 | 98.4 | 3489 | 4505 | [3153 ; 5857] |
3 | 2.5107 | 2.5068 | 98.5 | 4206 | 4505 | [3153 ; 5857] |
4 | 2.5003 | 2.5009 | 98.8 | 4390 | 4505 | [3153 ; 5857] |
5 | 2.5003 | 2.5044 | 98.8 | 5811 | 4505 | [3153 ; 5857] |
Description of key information
Key value for chemical safety assessment
Additional information
The registered substance is not considered to have oxidizing properties
Justification for classification or non-classification
Find below the oxidising properties result obtained for one similar substance (a comparable value is expected):
- The test item [similar substance 2] was not considered to have oxidizing properties in our experimental conditions.
The weight of evidence can be applied as the substances are very similar.
The registered substance is not considered to have oxidizing properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.