Bis(2-ethylhexyl) malate

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

22 November 2017 to 03/04/2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

11 July 2006

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: isothermal thermogravimetry

Test material

Test material information

Constituent 1

Reference substance name:

Bis(2-ethylhexyl) malate

EC Number:

260-070-5

EC Name:

Bis(2-ethylhexyl) malate

Cas Number:

56235-92-8

Molecular formula:

C20H38O5

IUPAC Name:

1,4-bis(2-ethylhexyl) 2-hydroxybutanedioate

Test material form:

liquid

Details on test material:

Identification: Dermol DOM
Appearance: Clear colourless to pale yellow liquid
Batch: P7677
Purity/Composition: >95%
Test item storage: At room temperature
Stable under storage conditions until: 31 December 2018 (retest date)
Additional information
Test Facility test item number: 209081/A
Purity/Composition correction factor: No correction factor required
Test item handling: No specific handling conditions required
Molecular structure: Not indicated
Molecular formula: C20H38O5
Molecular weight: 358.5

Specific details on test material used for the study:

Identification: Dermol DOM
Appearance: Clear colourless to pale yellow liquid
Batch: P7677
Purity/Composition: >95%
Test item storage: At room temperature
Stable under storage conditions until: 31 December 2018 (retest date)

Additional information
Test Facility test item number: 209081/A
Purity/Composition correction factor: No correction factor required
Test item handling: No specific handling conditions required
Molecular structure: Not indicated
Molecular formula: C20H38O5
Molecular weight: 358.5

Results and discussion

Vapour pressure

Vapour pressure 1

Key result

Test no.:

#1

Temp.:

ca. 20 °C

Vapour pressure:

ca. 0 Pa

Vapour pressure 2

Key result

Test no.:

#2

Temp.:

ca. 25 °C

Vapour pressure:

ca. 0 Pa

Any other information on results incl. tables

A representative weight loss curve of the test item is shown inFigure 3. The results of the isothermal TGA analysis for the test item and the vapour pressure at 20°Cand 25°Care given inTable 3andTable 4.

The vapour pressure regression curve of the log P_Tof the test item as function of the reciprocal temperatures is shown inFigure 4. The equation of the curve was:
log P_T= -6120´1/T + 16.7 (r = 0.995, n = 8).

Table 3          
Results of the Vapour pressure Isothermal TGA Analysis

Temperature [°C]	Weight loss [µg/min]	νT [g/cm^2/h]	logνT	logPT	PT [Pa]
90	0.672632	8.03´10^-5	-4.10	-0.11	0.78
	0.579031	6.91´10^-5	-4.16	-0.19	0.65
100	1.49599	1.79´10^-4	-3.75	-0.34	2.2
	1.29817	1.55´10^-4	-3.81	-0.26	1.8
110	3.29401	3.93´10^-4	-3.41	-0.78	6.0
	2.81497	3.36´10^-4	-3.47	-0.69	4.9
120	6.83816	8.16´10^-4	-3.09	1.18	15
	5.77528	6.89´10^-4	-3.16	1.09	12

 

Table 4          
Vapour Pressure of the Test Item

Temperature [°C]	logPT	PT [Pa]	PT [mm Hg]
20	-4.17	6.7´10^-5	5.0´10^-7
25	-3.82	1.5´10^-4	1.1´10^-6

Applicant's summary and conclusion

Conclusions:

The vapour pressure of the test substance was determined to be 0.000067 Pa at 20 °C and 0.00015 Pa at 25 °C, under the conditions of the test.

Executive summary:

In this guideline (OECD 104) study, [conducted with GLP certification], the vapour pressure of the test substance (EC 260-070-5) was determined to be 0.000067 Pa at 20 °C and 0.00015 Pa at 25 °C, under the conditions of the test.