Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 943-730-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Remarks:
- Summary of available data used for the endpoint assessment of the target substance
- Adequacy of study:
- key study
- Justification for type of information:
- Refer to analogue justification document provided in IUCLID section 13.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 12.1
- Sampling time:
- 23 d
- Remarks on result:
- other: source, CAS 68443-84-5,Nyco, 2012, CO2 evolution, RL1
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 18.5
- Sampling time:
- 29 d
- Remarks on result:
- other: source, CAS 68443-84-5,Nyco, 2012, CO2 evolution, RL1
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 28
- Sampling time:
- 60 d
- Remarks on result:
- other: source, CAS 68443-84-5,Nyco, 2012, CO2 evolution, RL1
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 4.6
- Sampling time:
- 60 d
- Remarks on result:
- other: source, CAS 84418-63-3, Nyco, 2012, CO2 evolution, RL2
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 14
- Sampling time:
- 28
- Remarks on result:
- other: source, CAS 647028-25-9, Croda, 2012, CO2 evolution, RL2
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
Reference
Description of key information
Not readily biodegradable: 4.6 - 28 % (CO2 evolution) in 60 days; read-across.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
No study investigating the biodegradation of Monopentaerythritol tetraesters and dipentaerythritol hexaesters of 2-ethylhexanoic and n-valeric acids. Therefore, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to the structurally related source substances Triisononanoic acid, triester with 2,2’-[oxybis(methylene)]bis[2- (hydroxymethyl)propane- 1,3-diol] tris(2-ethylhexanoate) (CAS 68443-84-5), Isononanoic acid, mixed esters with dipentaerythritol, heptanoic acid and pentaerythritol (CAS 84418-63-3) and Dipentaerythritol with fatty acids, C5 and C9 iso (CAS 647028-25-9) is applied.
Based on the high degree of similarity between the structural and physico-chemical properties of the target and source substances, the source substances are considered to be suitable representatives for the evaluation of the biodegradation of the target substance. The read-across approach is justified in detail within the analogue justification in IUCLID section 13.
The biodegradability of Triisononanoic acid, triester with 2,2’-[oxybis(methylene)]bis[2- (hydroxymethyl)propane- 1,3-diol] tris(2-ethylhexanoate) (CAS 68443-84-5), Isononanoic acid, mixed esters with dipentaerythritol, heptanoic acid and pentaerythritol (CAS 84418-63-3) and Dipentaerythritol with fatty acids, C5 and C9 iso (CAS 647028-25-9) was tested in a GLP guideline study following the specifications given by OECD guideline 301 B. The studies were conducted under aerobic conditions using domestic activated sludge as inoculum. During the incubation time of 60 and 28 days the degradation was followed by determining the CO2 production. A degradation rate of 28% was determined at test termination (60 days) for Triisononanoic acid, triester with 2,2’-[oxybis(methylene)]bis[2-(hydroxymethyl)propane- 1,3-diol] tris(2-ethylhexanoate) (CAS 68443-84-5), 4.6% at test termintation (60 days) for Isononanoic acid, mixed esters with dipentaerythritol, heptanoic acid and pentaerythritol (CAS 84418-63-3) and 14% after 28 days for Dipentaerythritol with fatty acids, C5 and C9 iso (CAS 647028-25-9), respectively. None of the source substancesis therefore considered as readily biodegradable according to the OECD criteria.
Based on the available results from structurally related source substances (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which are characterized by a similar environmental fate profile and comparable structure, it can be concluded that Monopentaerythritol tetraesters and dipentaerythritol hexaesters of 2-ethylhexanoic and n-valeric acids) is not readily biodegradable.
[Type of water: freshwater]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.