Registration Dossier
Registration Dossier
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EC number: 205-785-5 | CAS number: 151-13-3
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Remarks:
- skin irritation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
- Endpoint addressed:
- skin irritation / corrosion
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- clinical 48-hour patch test
- GLP compliance:
- no
Test material
Constituent 1
Method
- Ethical approval:
- not specified
- Remarks:
- informed consent likely obtained
- Details on study design:
- 48-hour closed patch test
- Exposure assessment:
- measured
- Details on exposure:
- 20% test material in petrolatum was applied to 32 healthy male volunteers (ages not given) in a 48-hour closed patch test.
Results and discussion
- Results:
- Skin irritation was not observed
Applicant's summary and conclusion
- Conclusions:
- kin irritation was not observed when ethyl ricinoleate (20% in petrolatum) was applied in a 48-hour closed patch test in 32 healthy male volunteers.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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