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EC number: 236-195-6 | CAS number: 13223-03-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18/08/1994-16/09/1994
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well documented report of a guideline study conducted to GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- yes
- Remarks:
- System was purged of CO2 after addition of the test substance and before addition of the inoculum in order to lower the endogenous respiration. Inorganic carbon (IC) was estimated by subtracting total organic carbon (TOC) from total carbon (TC).
- GLP compliance:
- yes (incl. QA statement)
Test material
- Details on test material:
- - Name of test material (as cited in study report): MADQUAT MC 75 (chlorure de methacryloxyethyltrimethylammonium )
- Physical state: clear yellowish liquid
- Analytical purity: 75 %
- Purity test date: 1994/07/25
- Lot/batch No.: M 67 Bis
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Domestic sewage treatment plant, Versailles, France
- Storage length: 24 h
- Preparation of inoculum for exposure: 4000g centrifugation for 20 mn at 20°C . Then adjustment to a concentration factor of 40.
- Pretreatment: aeration
- Concentration of sludge: 1%
- Initial cell/biomass concentration: 1,25 x 10 3 bact/ml, - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- ca. 48.7 mg/L
- Based on:
- DOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: 1% = 1.25 x 10 3 bact/ml
- Test temperature: 22 +/- 2°C
- pH: 7.4
- pH adjusted: no
- CEC (meq/100 g): 41
- Aeration of dilution water: air flow
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: 3000 ml glass flasks containing 1500 ml test medium
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: air flow
- Measuring equipment: Oxymetre, conductimetre, pH-rnetre : multifonctions apparatus Jenway 3410 , Carlo Erba automatic CO2 analyser, Dissoved CO2 analyser MAIHAK TOCOR 100
- Test performed in open system: no
- Details of trap for CO2 and volatile organics if used: Soude 5 M, hydroxyde de baryum 0,0125 M, acide chlorhydrique 0,05 M
SAMPLING
- Sampling frequency: on days 1, 4, 5, 8, 11, 15, 18, 22, 25, 28, 29
- Sampling method: CO2
STATISTICAL METHODS: none
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
- Test performance:
- Difference between the two replicates was less 20% at the 10 day window.
The biodegradation of the reference substance was less than 60% in 14 days.
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 46
- Sampling time:
- 4 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 61
- Sampling time:
- 8 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 70
- Sampling time:
- 15 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 71
- Sampling time:
- 21 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 69
- Sampling time:
- 28 d
- Details on results:
- Degradation peaked at 71% after 22 days. The lag phase (time to attain 10% degradation) was less than 5 days and degradation attained 70% 10 days later. The abiotic sterile control demonstrated that 33% abiotic degradation (physical or chemical) took place.
BOD5 / COD results
- Results with reference substance:
- Biodegradation was greater than 60% in 14 days.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- MADAMQUAT MC is considered to be readily biodegradable (69% in 28 days).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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