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Diss Factsheets

Physical & Chemical properties

Vapour pressure

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Administrative data

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Reference
Endpoint:
vapour pressure
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Study period:
January 21, 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Read across study
Justification for type of information:
Refer to section 13 of IUCLID for details on the read-across justification.
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: by loss of weight or by trapping vaporisate
Key result
Temp.:
ca. 20 °C
Vapour pressure:
ca. 0 Pa
Temp.:
ca. 25 °C
Vapour pressure:
ca. 0 Pa

The vapour pressure was calculated initially for three measurement points as below:

No.

temperature [0C]

vapour pressure [Pa]

1

82.9

0.26

2

99.3

1.69

3

113.6

9.46

The log(p) = a.1/T+b graph is shown in the attached background material section

Conclusions:
Under the study conditions, the vapour pressure was 1.51 x 10-5 Pa at 20°C and 3.79 x 10-5 Pa at 25°C.
Executive summary:

The vapour pressure of the test substance was determined according to OECD Guideline 404 and EU Method A.4. The method was based on the determination of the mass of test substance flowing out of a Knudsen cell in the form of vapour per unit of time, through a micro-orifice under ultra-vacuum conditions. Under the study conditions, the vapour pressure was 1.51 x 10-5 Pa at 20°C and 3.79 x 10-5 Pa at 25°C (Petryka, 2010).

Description of key information

The vapour pressure was determined according to OECD Guideline 404 and EU Method A.4 (Petryka, 2010). 

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

Value for the read across substance, amides, C8-18 (even numbered) and C18-unsatd., N-(hydroxyethyl).