Registration Dossier
Registration Dossier
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EC number: 213-914-1 | CAS number: 1066-40-6
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 21-day EC50 value of 0.30 mg/L has been determined for the effects of HMDS on reproduction of Daphnia magna. A 21-day NOEC of 0.08 mg/L, equivalent to 0.085 mg/l (time-weighted mean, derived by reviewer) has been determined for the same endpoint.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.085 mg/L
Additional information
A 21-d EC50 value of 0.30 mg/l (measured, arithmetic mean) and NOEC of 0.080 mg/l (measured, arithmetic mean, equivalent to 0.085 mg/l, time-weighted mean) have been determined for the effects of hexamethyldisiloxane (CAS 107-46-0) on reproduction of Daphnia magna. In view of the exposure regime it is likely that the test organisms were exposed primarily to the parent form of the tested substance, although some losses were observed based on measured concentrations in spent media.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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