Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 289-860-8 | CAS number: 90028-67-4 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Evernia furfuracea, Usneaceae.
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Based on a read-across from an experimental GLP study performed on an analogue substance according to the OECD 201 guideline, the following result has been extrapolated to the registered substance:
- 72h-ErL50 > 100 mg/L (nominal test item loading rate).
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 100 mg/L
Additional information
For that endpoint, a study on the registered substance was not available. Therefore, in order to assess the toxicity of the registered substance to algae, the results from an experimental OECD 201 study performed under GLP conditions on the analogue substance Treemoss concrete (Concrete obtained from lichen of Pseudevernia furfuracea (syn evernia furfuracea) (Parmeliaceae) by extraction with a mixture of polar and apolar solvents) have been used.
The details of this study are summarized below:
- Test item: TREE MOSS CONCRETE
- Test system: Pseudokirchneriella subcapitata
- Exposure duration: 72 hours
- Test concentrations: Control - 100 mg/L (limit test)
- Incubator: Temperature 22.8 – 23.3 °C ; shaking at 120 rpm; light intensity: 6461 Lux
- Measurement of cell growth: Beckman Coulter Z2 and Malassez counting cell
Results: The results obtained for the test item on the toxicological endpoint “inhibition of growth rate” indicate an ErL50-(0-72h) higher than the highest tested loading rate, i.e. 100 mg/L, based on nominal test item loading rate.
The results obtained for the test item on the toxicological endpoint “Yield inhibition” indicate an EyL50-(0-72h) higher than the highest tested loading rate, i.e. 100 mg/L, based on nominal test item loading rate.
Validity criteria: In the control, the increase of the biomass during 72 hours was determined to be higher than factor of 16. The coefficients of variation ofdaily section-by-section specific growth rateand ofaverage specific growth ratewere determined respectively to be less than 35% and 7% in the control. The validity criteria were successfully fulfilled.
This study complied with the guideline requirement and can therefore be considered acceptable for that endpoint. The read-across justification is provided in the related iuclid study record.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
