Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 235-595-8 | CAS number: 12336-95-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Pas applicable
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Toxicological review of trivalent chromium. In Support of Summary Information on the Integrated Risk Information System (IRIS
- Author:
- Grevatt PC
- Year:
- 1 998
- Bibliographic source:
- U.S. Environmental Protection Agency Washington, DC, USA, 51 p.
Materials and methods
- Objective of study:
- absorption
- distribution
- excretion
- metabolism
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 417 (Toxicokinetics)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Chromium trichloride
- EC Number:
- 233-038-3
- EC Name:
- Chromium trichloride
- Cas Number:
- 10025-73-7
- Molecular formula:
- Cl3Cr
- IUPAC Name:
- Chromium trichloride
- Test material form:
- solid: crystalline
Constituent 1
- Specific details on test material used for the study:
- Non disponible
- Radiolabelling:
- other: Dans certaines des études présentées seulement
Test animals
- Species:
- other: Différentes espèces utilisées selon l'étude décrite
- Strain:
- not specified
- Details on species / strain selection:
- Pas applicable
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- Pas applicable
Administration / exposure
- Route of administration:
- other: Voie d'administration différentes selon l'étude considérée
- Vehicle:
- not specified
- Details on exposure:
- Pas applicable
- Duration and frequency of treatment / exposure:
- Dépend de l'étude considérée
- No. of animals per sex per dose / concentration:
- Dépend de l'étude considérée
- Control animals:
- not specified
- Positive control reference chemical:
- Pas applicable
- Details on study design:
- Pas applicable
- Details on dosing and sampling:
- Pas applicable
- Statistics:
- Pas applicable
Results and discussion
- Preliminary studies:
- Pas applicable
Toxicokinetic / pharmacokinetic studies
- Details on absorption:
- Se référer au rapport Grevatt, 1998
- Details on distribution in tissues:
- Se référer au rapport Grevatt, 1998
- Details on excretion:
- Se référer au rapport Grevatt, 1998
Metabolite characterisation studies
- Metabolites identified:
- not specified
- Details on metabolites:
- Se référer au rapport Grevatt, 1998
Bioaccessibility (or Bioavailability)
- Bioaccessibility (or Bioavailability) testing results:
- Se référer au rapport Grevatt, 1998
Applicant's summary and conclusion
- Conclusions:
- Se référer au rapport Grevatt, 1998
- Executive summary:
Se référer au rapport Grevatt, 1998
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.