Registration Dossier
Registration Dossier
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EC number: 208-047-0 | CAS number: 506-61-6
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 01 November 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
- Principles of method if other than guideline:
- The method used is based on a procedure designed to comply with that given in 'Particle size distribution, fibre length and diameter distribution', June 1996 European Commission technical guidance document, which satisfies the requirements of OECD Guideline 110
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- sieving
- Type of particle tested:
- primary particle
- Type of distribution:
- mass based distribution
- No.:
- #1
- Size:
- < 100 µm
- Distribution:
- 16.8 %
- Conclusions:
- The proportion of potassium dicyanoargentate < 100 μm was 16.8%.
- Executive summary:
This is a GLP compliant study following OECD guideline 110 (Screening test) and is suitable for use as the key study for this endpoint. The proportion of potassium dicyanoargentate < 100 μm was 16.8%.
Reference
The results of the sieving procedure are shown below:
Measurement |
Result |
Mass of test item transferred to sieve |
10.24g |
Mass of test item passed through sieve |
1.72g |
Proportion of test item <100µm |
16.8% |
Description of key information
The proportion of potassium dicyanoargentate < 100 μm was 16.8%
Additional information
A GLP-compliant study following OECD guideline 110 (screening test) is available for this endpoint (Harlan Laboratories 2011) and is considered suitable for use as the key study. The proportion of potassium dicyanoargentate < 100 μm was 16.8%
The dustiness of potassium dicyanoargentate was tested in a modified Heubach procedure according to standard guideline (Selck and Parr 2012). The total dustiness was determined to be 90.92 mg/g (9.1%). The inhalable fraction was 52.94 mg/g (40.9 %), the thoracic fraction was 7.21 mg/ g (0.12 %) and the respirable fraction was 2.30 mg/g (0.11 %). The Mass Median Aerodynamic Diameter (MMAD) was determined to be 34.9 μm with a geometric standard deviation of 2.1 μm.
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