Silicic acid (H4SiO4), tetraethyl ester, reaction products with bis(acetyloxy)dioctylstannane

Endpoint summary

Additional information

Experimental studies investigating the short-term toxicity of the test item to aquatic organisms as well as to activated sludge microorganisms are available. All studies were performed under GLP conditions according to standard OECD guidelines. The test solutions for the aquatic studies were prepared as Water Accommodated Fractions (WAF) up to a limit of 100 mg/L, with the exception of the study on activated sludge microorganisms. No effects were recorded in any of the available studies up to the maximum loading rate resulting in E(L)L50 values of > 100 mg/L. The NOELR in the algae study was derived to be ≥ 100 mg/L. The substance and its hydrolysis products are not expected to have any impact on the degradation process in sewage treatment plants. No effects on respiration rate of activated sludge microorganisms were recorded up to a limit concentration of 1000 mg/L.
The test item is expected to hydrolyse rapidly in contact with water. The experimental determination of a hydrolytic half-life was technically not feasible since no analytical method could be established to adequately measure the substance concentrations in the buffer solutions (see also IUCLID section 5.1.2). Since rapid hydrolysis is assumed, the available studies assess the possible effects of the substance itself but also of the different hydrolysis products. Thus, it can be assumed that the test item and its hydrolysis products do not have any effects on aquatic organisms based on the results from the available studies.