Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-000-8 | CAS number: 90-51-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Reliability 1
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: scanning electron microscopy after the samples was fractionated by a 100 μm sieve
- Type of distribution:
- mass based distribution
Test material
- Reference substance name:
- 6-amino-4-hydroxynaphthalene-2-sulphonic acid
- EC Number:
- 202-000-8
- EC Name:
- 6-amino-4-hydroxynaphthalene-2-sulphonic acid
- Cas Number:
- 90-51-7
- Molecular formula:
- C10H9NO4S
- IUPAC Name:
- 6-amino-4-hydroxynaphthalene-2-sulphonic acid
Constituent 1
Results and discussion
- Mass median aerodynamic diameter:
- 4.88 µm
- Remarks on result:
- other: as spherical particles (Sieve Fraction nominal < 100μm)
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- < 4 µm
- Distribution:
- 0 %
- Remarks on result:
- other: respirable fraction; accounting based on the total sample weight
- No.:
- #2
- Size:
- >= 4 - < 10 µm
- Distribution:
- 0.04 %
- Remarks on result:
- other: thoracic fraction; accounting based on the total sample weight
- No.:
- #3
- Size:
- >= 10 - < 100 µm
- Distribution:
- 0.04 %
- Remarks on result:
- other: inhalable fraction; accounting based on the total sample weight
Applicant's summary and conclusion
- Conclusions:
- Particle size distribution was determined according to OECD 110 under GLP, so there is no reason to conclude that the results are not reliable. The study was assessed to be of high quality and testing is expected to be reasonably performed; results can be considered as reliable. The substance contains 0 % respirable particles (< 4 µm), 0.04 % thoracic particles (4-10 µm) and 0.04 % inhalable particles (10-100 µm).
- Executive summary:
The particle size distribution of the test substance was determined by scanning electron microscopy after the samples was fractionated by a 100 μm sieve according to OECD Guideline 110 (GLP).
Sieve Fraction
weighted sample: 1.0658 g
weight fraction < 100 μm: 0.0009 g
sieve mass fraction < 100 μm: 0.08 %
Mass Fraction
Sieve Fraction nominal < 100μm
Particle Size Spherical Volume Cubical volume < 4 µm (respirable) 4.30 % 6.46 % 4 -10 µm (thoracic) 49.00 % 56.93 % 10 -100 µm (inhalable) 46.70 % 36.61 % > 100 µm 0.0 % 0.0 % Median (diameter) 4.88 µm 4.35 µm Median diameter corresponds to MMAD (Mass Median Aerodynamic Diameter < 100μm).
Accounting based on the total sample weight:
Particle Size [µm] Spherical Volume [%] Mass Fraction > 100 99.92 Sieve Fraction > 100 0.00 Total (> 100 µm) 99.92 Sieve Fraction 10 -100 (inhalable) 0.04 Sieve Fraction 4 -10 (thoracic) 0.04 Sieve Fraction < 4 (respirable) 0.00
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.