Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 701-135-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Stability
Due to the complex nature of the test material, it was considered that determination of the hydrolytic stability according to Method C7 Hydrolysis as a Function of pH of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004 was not feasible. The hydrolytic stability of the main constituents was estimated using the specialist estimation software, HYDROWIN v2.00 (September 2010), © 2000 U.S. Environmental Protection Agency. Overall, it was considered that the test item would be essentially stable towards hydrolysis (half-life greater than 1 year at 25°C) at pH 4, 7 and 9.
Biodegradation
Given the results of the three OECD TG screening tests for biodegradation in water were inconclusive, an OECD 309 biodegradation in surface water, simulation study, was conducted. The resulting DT50 values were 12.6 days (at 10 µg/L) and 16.2 days (at 100 µg/L). The substance degraded to up to eight major unidentifiable degredates (10.4–37.0% AR). In addition, eleven minor unidentified degredates were present at low levels (≤7.3% AR).
The substance can be considered biodegradable.
Bioaccumulation
Low potential for bioaccumulation in aquatic species was observed in an OECD 305 study. For the test substance itself, the growth corrected-lipid normalized biomagnification factor (BMFKgl) was calculated to be 0.023 with a half-life of approximately 5.5 days. For the main metabolite (M8), the growth corrected-lipid normalized biomagnification factor (BMFKgl) was calculated to be 0.027 with a half-life of approximately 1.05 days. The estimated BCFs are below the bioaccumulation triggers for a bioaccumulative (“B”: 2000 L/kg) or very bioaccumulative (“vB”: 5000 L/kg) substance.
Distribution
The organic-carbon partition (Koc) of the test item was determined to be in the range less than 17.8 to 1.63 x 10^3, log10 Koc in the range less than 1.25 to 3.21. These values indicate that the test item would have a range of mobility from very high to low according to McCall et al.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.