Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 680-798-0 | CAS number: 886577-76-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 Jun - 07 Jul 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Staatliches Gewerbeaufsichtsamt Hildesheim
Test material
- Reference substance name:
- 2-isocyanato-2-methyl-3-(prop-2-enoyloxy)propyl prop-2-enoate
- Cas Number:
- 886577-76-0
- Molecular formula:
- C11H13NO5
- IUPAC Name:
- 2-isocyanato-2-methyl-3-(prop-2-enoyloxy)propyl prop-2-enoate
- Test material form:
- liquid
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Municipal sewage treatment plant, 31137 Hildesheim, Germany- Initial cell/biomass concentration: Approx. 1.30 x 10E+07 cfu/L in the final test solution- Pretreatment: Activated sludge was washed twice with chlorine free tap water; settled sludge resuspended in mineral salts medium; maintained under aerobic condition by aeration for 2 h; homogenized with a blender; after sedimentation the supernatant decanted and maintained under aerobic conditions by aeration with CO2-free air for 6 days; 10 mL/L used to initiate inoculation
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 36 mg/L
- Based on:
- test mat.
- Remarks:
- corresponding to an oxygen demand of 52.2 mg O2/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS- Composition of medium: Mineral salts medium according to OECD 301 F- Test temperature: 20 - 24 °C- pH: 7.57 - 7.83- pH adjusted: no- Dispersion treatment: Continuous stirring- Continuous darkness: yesTEST SYSTEM- Measuring equipment: OxiTop system- Test performed in closed vessels: yes- Details of trap for CO2 and volatile organics if used: Soda limeSAMPLING- Sampling frequency: Continuous measurement (360 measuring points during the 28 days; every 112 min one measurement)CONTROL AND BLANK SYSTEM- Inoculum control: yes (with 2 replicates)- Toxicity control: yes- Functional control: yes
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 32
- Sampling time:
- 28 d
- Details on results:
- In the toxicity control (36 mg/L test item and 45 mg/L sodium benzoate) the biodegradation achieved 59% after 14 days. After 28 days the biodegradation came to 69%. The validity criterion that the test item should not inhibit the biodegradation of the reference item was fulfilled.
BOD5 / COD results
- Results with reference substance:
- The adaptation phase changed to degradation phase within 1 day (degradation > 10 %) and the biodegradation came to a maximum of 100 % on day 27. The pass level for ready biodegradation (> 60% degradation) was reached on day 2. The validity criterion that the degradation should be> 60% after 14 d was fulfilled.
Any other information on results incl. tables
Table 1: Degradation of test substance, functional- and toxicity control
Biodegradation (%) | ||||
|
Day 7 |
Day 14 |
Day 21 |
Day 28 |
Replicate 1 Test Item 36 mg/L Replicate 2 | 7 | 15 | 21 | 26 |
9 | 25 | 31 | 37 | |
Functional Control 45 mg/L | 87 | 94 | 97 | 100 |
Toxicity Control 36 mg/L Test Item + 45 mg/L Reference Item | 46 | 59 | 66 | 69 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- not readily biodegradable: 32% after 28 d (OECD 301F)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.