Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 266-405-1 | CAS number: 66557-45-7
Endpoint summary
Administrative data
Description of key information
The LD50 in rat (male/female, oral, gavage) was determined >5000 mg/kg bw for the target Disperse Violet 93.1 Br. Disperse Violet 93.1 Cl is not considered to be acutely toxic either. The substance is not classifiable according to CLP criteria.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
In three separate studies, the acute oral toxicity of Disperse Violet 93:1 Br in the rat was tested at a dose level of 5000 mg/kg body weight in 3 or 5 male and 3 or 5 female rats according to or equivalent to OECD Test Guideline 401. No lethality occurred after application of 5000 mg/kg body weight. Development of body weight was not impaired. The animals killed at the end of the observation period showed no macroscopically visible changes. Based on the results obtained in this study the median lethal dose value (LD50) of the substance for the male and female rat is greater than 5000 mg/kg body weight.
Justification for classification or non-classification
LD50 > 5000 mg/kg bw, not classifiable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
