Registration Dossier
Registration Dossier
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EC number: 700-042-6 | CAS number: 177997-13-6
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Data waiving:
- other justification
- Justification for data waiving:
- other:
- Justification for type of information:
- An animal study was considered unjustified for basic toxicokinetics. Instead an assessment of toxicokinetic behaviour was made based on all the available information on the substance. This is in accordance with Annex VIII of REACH which states in toxicokinetics "Assessment of the toxicokinetic behaviour of the substance to the extent that can be derived from the relevant available information". Please see section 13 'Assessment Reports' for the assessment of toxicokinetic behaviour.
Data source
Materials and methods
Test material
- Reference substance name:
- Nickel
- EC Number:
- 231-111-4
- EC Name:
- Nickel
- Cas Number:
- 7440-02-0
- Molecular formula:
- Ni
- IUPAC Name:
- nickel
- Reference substance name:
- Cobalt
- EC Number:
- 231-158-0
- EC Name:
- Cobalt
- Cas Number:
- 7440-48-4
- Molecular formula:
- Co
- IUPAC Name:
- cobalt(2+)
- Reference substance name:
- Lithium
- EC Number:
- 231-102-5
- EC Name:
- Lithium
- Cas Number:
- 7439-93-2
- Molecular formula:
- Li
- IUPAC Name:
- lithium
- Reference substance name:
- Aluminium
- EC Number:
- 231-072-3
- EC Name:
- Aluminium
- Cas Number:
- 7429-90-5
- Molecular formula:
- Al
- IUPAC Name:
- aluminum
- Test material form:
- solid: particulate/powder
- Details on test material:
- Composition represents the lowest and highest possible concentration of each individual constituent in NCA (estimated by Monte Carlo simulation, taking into account the following ranges of variability:
Sum of of Ni+Co+Al = approx. 1
Li =0.9-1.3
Ni: 0.75-0.99
Co: 0.01-0.2
Al: 0.01-0.2
A more detailed composition can be provided by the data holder, but is not defined in this record as this represents sensitive business information that cannot be shared with co-registrants. The composition, however, fits into the agrees Substance Identity Profile.
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
