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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-07-12 to 2019-10-21
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
adopted October 02, 2012
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
31 May 2008
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
Version / remarks:
June 2002
GLP compliance:
no
Type of method:
air comparison pycnometer (for solids)

Test material

Constituent 1
Chemical structure
Reference substance name:
ethyl 5-amino-1-[(2-fluorophenyl)methyl]-1H-pyrazole-3-carboxylate
EC Number:
805-733-7
Cas Number:
256504-39-9
Molecular formula:
C13H14FN3 O2
IUPAC Name:
ethyl 5-amino-1-[(2-fluorophenyl)methyl]-1H-pyrazole-3-carboxylate
Test material form:
solid

Results and discussion

Densityopen allclose all
Key result
Type:
density
Density:
1.335 g/cm³
Temp.:
20 °C
Type:
relative density
Density:
1.335
Temp.:
20 °C

Applicant's summary and conclusion

Conclusions:
The relative density of Aminopyrazol was determined to be 1.335.
Executive summary:

Title:

Aminopyrazol: Determination of the Relative Density

Purpose:

The purpose of the study was to determine the relative density of Aminopyrazol at a specific temperature by means of a gas comparison pycnometer.

 

Guidelines/Recommendations:        This study was based on the procedures indicated by the following internationally accepted guidelines and recommendations:

-Commission Regulation (EC) No.440/2008 laying down test methods pursuant to Regulation (EC) No.1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) (originally published as Council Regulation (EC) No.440/2008, corrigendum according to Official Journal of the European Union (EN) dated June 3, 2008, L 143/55), Annex, Part A, A.3.: “Relative Density”, Official Journal of the European Union, L 142, Volume 51, 31 May 2008

-Organisation for Economic Co-operation and Development (OECD), OECD Guidelines for Testing of Chemicals, Guideline No. 109, “Density of Liquids and Solids”, adopted October 02, 2012

-Product Properties Test Guideline OPPTS 830.7300 of the United States Environment Protection Agency (EPA), June 2002

 

Results:

The relative density of Aminopyrazol was determined using the gas comparison method at a temperature of 20 °C ± 1 °C.

The determination of the relative density was performed by three-fold measurements of two independent test item samples. The individual readings are summarised in Table 1.

The density of Aminopyrazol was determined to be 1.335 g/cm³ (= 1335 kg/m³) at 20 °C ± 1 °C.     

Conclusion:

In conclusion, the relative density of Aminopyrazol was determined to be 1.335. This study is classified acceptable and satisfies the guideline requirements for relative density studies.