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EC number: 202-311-9 | CAS number: 94-18-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Acute toxicity test was performed on fish for 96 hrs at 5 different concentrations according to the OECD guideline 203.10 fishes of 10 days old were used in 100 ml beaker. Half of the paraben solution was replaced every 24 h. Specific environmental condition was maintained and LC 50 value was determined.After experiment it was observed that the LC 50 value for benzylparaben(94-18-8) to fish was found to be 0.73mg/l concentrations.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.73 mg/L
Additional information
Various studies were reviewed along with the prediction data to evaluate the effect of the test compound on toxicity to fish. These are summarized as follows:
Acute toxicity test was performed on fish for 96 hrs at 5 different concentrations according to the OECD guideline 203.10 fishes of 10 days old were used in 100 ml beaker. Half of the paraben solution was replaced every 24 h. Specific environmental condition was maintained and LC 50 value was determined.After experiment it was observed that the LC 50 value for benzylparaben(94-18-8) to fish was found to be 0.73mg/l concentrations.
From peer reviewed journal the short-term toxicity to Pimephales promelas was performed for 48 hrs at five nominal concentrations in a temperature-controlled incubator at 24°C with a 16:8 light: dark cycle.500 ml beaker was taken having 250 ml of test chemical. Test solution was prepared by dissolved in high-performance liquid chromatography grade acetone and delivered into RHW at 0.1% acetone. No aeration was used and LD 50 value was determined at 24 and 48 hrs. On the basis of above experiment result the LD 50 value for Pimephales promelas for benzylparaben (94-18-8) was found to be 3.3 mg/L concentration.
The short term toxicity to fish test was performed on Oryzias latipes according to the OECD guideline 203. Fish was bred, acclimatized and exposed to atleast six different concentrations in a 100 ml beaker. Half of the test solution was replaced every 24 hrs. Mortality was measured and LC50 value was determined using probit conversion analysis.
According to the observations the LC 50 value for benzylparaben (94-18-8) to Oryzias latipes was found to be 0.72 mg/l concentration.
From above mentioned supporting studies the target chemicalbenzylparaben(CAS No 94-18-8), the majority values are indicative that the chemical is likely to cause aquatic fish toxicity.
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