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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 473-130-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
A limit test was conducted to determine the acute toxicity of the test substance to Daphnia magna according to EU Method C.2, in compliance with GLP. In this test, 2 replicates of 10 Daphnia magna neonates were exposed to the test substance at a nominal concentration of 100 mg/L under static conditions for 48 h. Immobility was recorded at 24 and 48 h. The analytical concentration of the test substance was measured by HPLC method and was found to be 100% of the nominal value at 0 h, and 98.8% of the nominal value at 48 h. Under the test conditions, the 48 h EC50 and NOEC of the test substance were >100 mg/L and ≥100 mg/L (nominal concentrations) respectively (Weyers, 2006a).
A study was conducted to determine the acute toxicity of the test substance to the algae Desmodesmus subspicatus according to EU Method C.3, in compliance with GLP. Triplicate inocula of the algae were exposed to nominal concentrations of the test substance (0.9, 1.9, 4.3, 9.4, 20.7, 45.5 and 100 mg/L) for 72 h under static conditions. Quantification of the applied concentrations was carried out using HPLC. The measured concentrations of the test substance ranged from 99.5-103% of nominal values at 0 h, and from 101.5 - 109.7% of nominal values at 72 h respectively. The cell densities were measured at 24, 48 and 72 h. Inhibition of the algal population was measured as reduction in growth and growth rate, relative to control cultures grown under identical conditions. Under the conditions of the study, the 72 h EbC10 (biomass) and ErC10 (growth rate) were determined to be 4.8 and 22.8 mg/L respectively; the EbC50 and ErC50 were determined to be 33.9 and 147 mg/L respectively; and the NOECs for biomass and growth rate were determined to be 1.9 and 4.3 mg/L respectively (Weyers, 2006b).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.