Registration Dossier
Registration Dossier
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EC number: 228-036-4 | CAS number: 6092-54-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Key value for chemical safety assessment
Additional information
Data on the toxicity of hexyl chloroformate to microorganisms is available from an activated sludge respiration inhibition study according to OECD guidance 209 (BASF, 1980). From this study 3 -h EC10 and 3 -h EC50 values were determined to be 140 mg/L and 340 mg/L, respectively.
As hexyl chloroformate is expected to rapidly hydrolyse in contact with water to form hexanol (CAS 111 -27 -3), hydrogen chloride (CAS 7647-01-0) and carbon dioxide (CAS 124-38-9), key information on the hydrolysis products was gathered also.
For the hydrolysis product hexanol microorganism toxicity data are available from a study by Bringmann and Kühn (1980). From this study with Pseudomonas putida a 16 -h toxicity threshold concentration (TTC) of 62 mg/L was derived. Although study details from the OECD report are lacking, it gives indication of limited toxicity to aquatic microorganisms.
For both the hydrolysis products hydrogen chloride and carbon dioxide no data on the toxicity to microorganisms are available.
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