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EC number: 635-156-4 | CAS number: 109293-98-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Key (acute):
The dietary LC50 value for northern bobwhite exposed to the test substance (diflufenzopyr) Technical was determined to be greater than 5620 ppm active a.i. the highest concentration tested. The no mortality and no observed effect concentration was 5620 ppm a.i., the highest concentration tested.
Key (reproduction):
The no-observed-effect concentration for northern bobwhite exposed to the test substance (diflufenzopyr) in the diet during this study was 1000 ppm a.i., the highest concentration tested.
Key value for chemical safety assessment
Additional information
Key (dietary):
A Dietary LC50 Study with the Northern Bobwhite was performed according to Section 71-2 of the Environmental Protection Agency Registration Guidelines Pesticide Assessment Guidelines, FIFRA Subdivision E, Hazard Evaluation: Wildlife and Aquatic Organisms; OECD Guideline 205, and ASTM Standard E857-87. The nominal dosages were: 562, 1000, 1780, 3160, and 5620 ppm a.i. The dietary LC50 value for northern bobwhite exposed to the test substance (difluenzopyr) Technical was determined to be greater than 5620 ppm active a.i. the highest concentration tested. The no mortality and no observed effect concentration was 5620 ppm a.i., the highest concentration tested.
Supporting (acute):
An Acute Oral Toxicity Study with the Northern Bobwhite was performed in accordance with Section 71-1 of the Environmental Protection Agency Registration Guidelines Pesticide Assessment Guidelines, FIFRA Subdivision E, Hazard Evaluation: Wildlife and Aquatic Organisms. The nominal dosages were: 292 , 486, 810, 1350 & 2250 mg a.i./kg.
The acute oral LD50 value for northern bobwhite exposed to the test substance (difluenzopyr) as a single oral dosage was determined to be greater than 2250 mg a.i./kg, the highest dosage tested. The no mortality and the no observed effect level were 2250 mg a.i./kg.
Supporting (dietary):
A Dietary LC50 Study with the Mallard was performed in accordance with Section 71-2 of the Environmental Protection Agency Registration Guidelines Pesticide Assessment Guidelines. FIFRA Subdivision E. Hazard Evaluation: Wildlife and Aquatic Organisms; OECD Guideline 205, and ASTM Standard E857-87 "Standard Practice for Conducting Subacute Dietary Toxicity Tests with Avian Species". The nominal dosages were 562, 1000, 1780, 3160 and 5620 ppm a.i. The dietary LC50 value for mallards exposed to the test substance (difluenzopyr) Technical was determined to be greater than 5620 ppm a.i., the highest concentration tested. The no mortality concentration was 5620 ppm a.i., the highest concentration tested. The no observed effect concentration was 3160 ppm a.i., based on the possible slight reduction in body weight among birds at 5620 ppm a.i.
Key (reproduction):
A reproduction study with the northern bobwhite was conducted in accordance with Environmental Protection Agency's Registration Guidelines Pesticide Assessment Guidelines, FIFRA Subdivision E, Hazard Evaluation: Wildlife and Aquatic Organisms, Subsection 71-4; OECD Guideline 206; and the ASTM "Standard Practice for Conducting Reproductive Studies with Avian Species".
The exposure period was ca. 20 weeks. The nominal test concentration were: 0, 160, 400, and 1000 ppm a i.
There were no treatment-related mortalities, overt signs of toxicity, or effects upon adult body weight or feed consumption at any of the concentrations tested. Additionally, there were no treatment related effects upon reproductive performance at the 160, 400 and 1000 ppm a.i. test concentrations. The no-observed-effect concentration for northern bobwhite exposed to diflufenzopyr in the diet during this study was 1000 ppm a.i., the highest concentration tested.
Supporting (reproduction)
A reproduction study with the mallard was conducted in accordance with Environmental Protection Agency's Registration Guidelines Pesticide Assessment Guidelines, FIFRA Subdivision E, Hazard Evaluation: Wildlife and Aquatic Organisms, Subsection 71-4; OECD Guideline 206; and the ASTM "Standard Practice for Conducting Reproductive Studies with Avian Species".
The exposure period was ca. 21 weeks. The nominal test concentration were: 0, 160, 400, and 1000 ppm a i.
There were no treatment-related mortalities, overt signs of toxicity, or effects upon adult body weight or feed consumption at any of the concentrations tested. Additionally, there were no treatment-related effects upon reproductive performance at the 160, 400 and 1000 ppm a.i. test concentrations. The no-observed-effect concentration for mallard exposed to the test substance (diflufenzopyr) in the diet during this study was 1000 ppm a.i., the highest concentration tested.
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