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EC number: 236-671-3 | CAS number: 13463-41-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
Additional information
The information contained within this robust summary document comes from studies which are in the ownership of Arch Chemicals Inc. and which are protected in several regions globally. This information may not be used for any purpose other than in support of the Chemical safety Report submitted by Arch Chemicals Inc. under Regulation EC 1907/2006.
Zinc pyrithione was not readily biodegradable under the conditions of the OECD 301B CO2evolution test (Table 4.4). Degradation to CO2reached 17% after 8 days, 39% after 28 days, and 54% after 43 days. This was below the pass level of 60% within a 10-day window within the 28-day test period. This data indicate that zinc pyrithione may be inherently biodegradable.
Sodium pyrithione, which is completely ionized in water, was shown to be readily biodegradable under the conditions of OECD 301B (see Table 4.4). This implies that zinc pyrithione would also be readily biodegradable at concentrations lower than those required for the OECD 301B test because zinc pyrithione is mostly dissociated to the free pyrithione and zinc ions at low concentrations in water. Refer to the low-level photolysis study for a comparison of the UV spectra of sodium pyrithione and zinc pyrithione at low concentration.
The major non transient metabolite, pyridine sulphonic acid, was also shown to be readily biodegradable under the conditions of OECD 301B.
The results of these studies suggest that zinc pyrithione would be at least inherently biodegradable; however, a guideline inherent biodegradability test was not done because other data on the degradation of zinc pyrithione exist from higher-level simulation tests conducted with radiolabelled test substance in natural water and natural water/sediment systems.
Table 4.4: Ready Biodegradability of ZnPT, NaPT, and the primary non-transient degradation product 2-Pyridine sulphonic acid (PSA)
Guideline / |
Test type1 |
Test parameter |
Inoculum |
Addit-ional substr. |
Test substance concentr. |
Degradation |
Reference |
|||
Type |
Concentration |
Adaptation |
Incubation period |
Degree |
||||||
OECD guideline 301B |
ready |
CO2evolution |
Activated sludge |
30 mg dry material per litre |
No |
No |
ZnPT 13.2 mg/L (5 mg C/L) |
28 d |
17 % degradation after 6 days, 49 % degradation after 29 days |
Clarke (2002) Unpublished study |
92/69/EEC, C.4-C. |
ZnPT 10 mg/L |
43 d |
17 % degradation after 8 days, 54 % degradation after 43 days |
Jenkins (1998) Unpublished study |
||||||
OECD guideline 301B |
PSA 26.5 mg/L (10 mg C/L) |
29 d |
49 % degradation after 6 days, 64 % degradation after 14 days 73 % degradation after 28 days |
Clarke (2002) Unpublished study |
||||||
OECD guideline 301B |
NaPT 30.2 mg/L (5 mg C/L) |
28 d |
0 % degradation after 6 days, 24 % degradation after 20 days 79 % degradation after 28 days |
Clarke (2002) Unpublished study |
1Test oninherentorreadybiodegradability according to OECD criteria
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