Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 227-231-1 | CAS number: 5726-19-2
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: invertebrate
- Data waiving:
- other justification
- Justification for data waiving:
- the study does not need to be conducted because the substance has a low potential for bioaccumulation based on log Kow <=3
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
In accordance with Column 2 of REACH Annex IX, the study does not need to be conducted since the substance has a low potential for bioaccumulation (log Pow < 3). - Endpoint:
- bioaccumulation in aquatic species: invertebrate
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Principles of method if other than guideline:
- Calculation by EPI-Suite, EPA (USA) / BCFBAF v3.01
- GLP compliance:
- no
- Type:
- BCF
- Value:
- 48.55 L/kg
- Basis:
- other: estimated by BCFBAF v3.01 (EPI Suite)
- Remarks on result:
- other: Log BCF from regression-based method = 1.686
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The estimated bioaccumulation factor for 2-methylcyclohexyl acetate was 48.55 L/kg wet-wt (BCFWIN v3.01).
- Executive summary:
The bioaccumulation factor was estimated by the calculation method EPI Suite / BCFWIN v3.01. The BCF for 2 -methylcyclohexyl acetate was calculated to be 48.55 L/kg wet-wt (BCFWIN v3.01). The Log BCF from regression-based method was 1.686.
Referenceopen allclose all
The estimated bioaccumulation factor was 48.55 L/kg wet-wt (BCFWIN v3.01). The Log BCF from regression-based method was 1.686. The log Pow used is 3.06 (expkow database).
Description of key information
Data waiving (Study scientifically not necessary): In accordance with Column 2 of REACH Annex IX, the study does not need to be conducted since the substance has a low potential for bioaccumulation (log Pow < 3).
Key value for chemical safety assessment
Additional information
Data waiving (Study scientifically not necessary): In accordance with Column 2 of REACH Annex IX, the study does not need to be conducted since the substance has a low potential for bioaccumulation (log Pow <3).
Supporting study: The estimated bioaccumulation factor for 2-methylcyclohexyl acetate was 48.55 L/kg wet-wt (BCFWIN v3.01).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
