Registration Dossier
Registration Dossier
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EC number: 277-362-3 | CAS number: 73296-89-6
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The PBT assessment for CAS 73296-89-6 is based on the criteria set out in the "Guidance on information requirements and chemical safety assessment, Chapter R.11: PBT Assessment" (ECHA, 2008).
Persistence (P) Assessment:
A substance is not considered to be persistent if it can be demonstrated that it has potential to degrade (via photolysis, hydrolysis and/or biodegradation). Several studies using standardized test guidelines could demonstrate the ready biodegradability of the substance (100% after 28 days based on CO2 evolution, OECD 301 B). Therefore, CAS 73296-89-6 does not meet the Persistent (P) or very Persistent (vP) criteria.
Bioaccumulation (B) Assessment:
The value of log Pow at 20 ºC is ≤ -2.1. Available data indicate that CAS 73296-89-6 has a very low potential for bioconcentration and the substance will not accumulate to significant levels in the aquatic environment. Therefore, CAS 73296-89-6 does not meet the Bioaccumulative (B) or very Bioaccumulative (vB) criteria.
Toxicity (T) Assessment:
Environmental Toxicity:
According to Annex XIII of REACH Regulation (EC) No 1907/2006, a substance is considered to be toxic in terms of PBT criteria if long-term NOEC values for aquatic organisms are lower than 0.01 mg/L. The NOEC value based on chronic experimental data on daphnids was 0.479 mg/L. This value exceeds the toxicity criterion and therefore, CAS 73296-89-6 is not considered as a toxic substance regarding ecotoxicological endpoints.
Human Health Toxicity:
Carcinogenicity: the available data on CAS 73296-89-6 do not warrant classification for carcinogenicity under Directive 67/548/EEC or GHS/CLP.
Mutagenicity: the available data indicate that CAS 73296-89-6 is not genotoxic or mutagenic and do not warrant classification for carcinogenicity under Directive 67/548/EEC or GHS/CLP.
Reproductive Toxicity: there is no evidence that CAS 73296-89-6 causes reproductive or developmental toxicity. The available data indicate that members of the alkyl sulfate category are not toxic to reproduction and do not warrant classification under Directive 67/548/EEC or GHS/CLP.
Chronic toxicity: due to the results of the relevant mammalian toxicity studies CAS 73296-89-6 is not classified as Xn, R48 or STOT RE.
The substance is considered not to be PBT or vPvB on the basis of the provided relevant data.
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