Benzyl butyl phthalate

Additional information on environmental fate and behaviour

Administrative data

Endpoint:

additional information on environmental fate and behaviour

Type of information:

experimental study

Adequacy of study:

key study

Study period:

April 7, 1986 - May 7, 1986

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: GLP compliant, microcosm study, available as unpublished report, acceptable with restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1986

Report date:

1986

Materials and methods

Principles of method if other than guideline:

30-day freshwater microcosm study to measure the biodegradability of butyl benzyl phthalate

GLP compliance:

yes

Type of study / information:

This robust summary concerns this study's identifiation of the biodegradation products of the test substance

Test material

Test material information

Constituent 1

Reference substance name:

butyl benzyl phthalate

IUPAC Name:

butyl benzyl phthalate

Details on test material:

- Name of test material (as cited in study report): butyl benzyl phthalate (BBP)
- Physical state: Clear Liquid
- Analytical purity: 98.6%
- Lot/batch No.: DD243
- Radiochemical purity (if radiolabelling): 94.4% of 14C activity contained in the BBP peak
- Locations of the label (if radiolabelling): Phthalate ring.
- Storage condition of test material: -10 °C

Results and discussion

Any other information on results incl. tables

Only one peak identified on HPLC chromatograms attributable to metabolites. This was visible in samples collected on days 1 or 2.

This peak is attributable to monobutyl phthalate and/or monobenzyl phthalate (these substances could not be spectrally distinguished)

This peak is not found is spectrograms of samples taken on day 22, or in samples which were stored in a refrigerator till 60 days after the end of the experiment before analysis.

This suggests that the metabolites degrade rapidly.

Applicant's summary and conclusion

Conclusions:

The only metabolites of benzyl butyl phthalate identified were monobutyl phthalate and/or monobenzyl phthalate (these substances could not be spectrally distinguished). The metabolites were found to degrade rapidly.

Executive summary:

In a non-guideline, non-GLP study on the biodegradation of benzyl butyl phthalate the only metabolites identified were monobutyl phthalate and/or monobenzyl phthalate (these substances could not be spectrally distinguished). The metabolites were found to degrade rapidly.