Registration Dossier
Registration Dossier
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EC number: 248-670-5 | CAS number: 27816-23-5
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
- Justification for type of information:
- Test not performed because 2-methoxyethyl 2-cyanoacrylate is highly reactive to water resulting in fast polymerization process (in seconds) thus the nature of the substance does not allow to be tested (Annex XI, section 2). As it is described in the Guidance on information requirements and chemical safety assessment Chapter R.5: Adaptation of information requirements chapter (R.5.2.2 Testing is technically not possible (page 28)) the waiver is herewith justified.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Executive summary:
Stability testing demonstrated that 2 -methoxyethyl 2 -cyanoacrylate is a reactive molecule which polymerizes immediately on contact with moisture. Due to the compound’s high reactivity, basic toxicokinetics of the monomer cannot be determined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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