Registration Dossier
Registration Dossier
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EC number: 211-754-7 | CAS number: 693-57-2
Endpoint summary
Administrative data
Description of key information
Additional information
6.1.1 Short-term toxicity to fish
The acute toxicity of the test material to the freshwater fish rainbow trout (Oncorhynchus mykiss) was investigated and gave a 96-Hour LC50 of greater than 100 mg/L. The test was conducted in accordance with the OECD Guidelines for Testing of Chemicals (1992) No 203, "Fish, Acute Toxicity Test" referenced as Method C.1 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC), US CFR Title 40 Part 797 Section 1400: US EPA Pesticide Assessment Guideline, Sub-Division E Section 72-1 and US EPA Draft Ecological Effects Test Guideline OPPTS 850.1075.
The study was performed under GLP in line with accepted standardised guidelines with a high standard of reporting. The study was assigned a reliability score of 1 according to the principles for assessing data quality set out in Klimisch (1997) and is considered suitable for assessment as an accurate reflection of the test material.
6.1.3 Short-term toxicity to aquatic invertebrates
The toxicity of the test material to Daphnia magna was investigated in accordance with the standardised guidelines OECD 202, EU Method C.2, US CFR Title 40 Part 797 Section 1300: US EPA Pesticide Assessment Guideline, Sub-Division E Section 72-2 and US EPA Draft Ecological Effects Test Guideline OPPTS 850.1010.
Under the conditions of the study, the 48-Hour EC50 was determined to be greater than 100 mg/L. Correspondingly the No Observed Effect Concentration was determined to be 100 mg/L.
The study was performed under GLP in line with accepted standardised guidelines with a high standard of reporting. The study was assigned a reliability score of 1 according to the principles for assessing data quality set out in Klimisch (1997) and is considered suitable for assessment as an accurate reflection of the test material.
6.5.1. Toxicity to aquatic algae and cyanobacteria
The effect of the test material on the growth of Pseudokirchneriella subcapitata was investigated in accordance with the standardised guidelines OECD 201, EU Method C.3, US CFR Title 40 Part 797 Section 1050, US EPA Pesticide Assessment Guidelines, Sub-Division J, Section 122-2 and the US EPA Draft Ecological Effects Test Guideline OPPTS 850.5400.
The effects on growth of were investigated over a 96 -hour period and gave an ErC50 (0 - 72 h) of 22 mg/L, an EyC50 (0 - 72 h) of 8.1 mg/L and an EbC50 (0 - 72 h) of 8.5 mg/L.
Based on the geometric mean measured test concentrations the ErC50 (0 - 72 h) value was 20 mg/L; the EyC50 (0 - 72 h) value was 7.0 mg/L and the EbC50 (0 - 72 h) value was 7.4 mg/L.
The study was performed under GLP in line with accepted standardised guidelines with a high standard of reporting. The study was assigned a reliability score of 1 according to the principles for assessing data quality set out in Klimisch (1997) and is considered suitable for assessment as an accurate reflection of the test material.
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