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EC number: 217-775-8 | CAS number: 1951-97-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Appearance/physical state/colour
On the basis of physical observation and using the sense of smell piperazine, compound with phosphoric acid was found to be a crystalline colorless solid with characteristic odor
Melting point/freezing point
The experimental value of the melting point for the substance piperazine, compound with phosphoric acid was obtained as 240 deg C at 970 hPa . There was no decomposition or sublimation of the substance. This value at 101 325 Pa is equivalent to 250.70o C.
Boiling point
The boiling point of the substance piperazine, compound with phosphoric acid was obtianed at 460o C at 760 mm Hg (101 323 Pa). There was no decomposition of the substance.
Density
The bulk density of piperazine, compound with phosphoric acid by the mass by volume method was found to be 0.693 g/cm3 at room temperature of 37 deg C. AT standard temerature of 20oC the density is equivalent to 1.282 g/cm3. Thus, the relative density at 20oC is equivalent to 1.282
Particle size distribution (Granulometry)
The particle size distribution (granulometry) of piperazine, compound with phosphoric acid gave the majority particle size as ranging between 150 to 250 micrometer. Thus, it can be concluded that there is no scope of exposure to inhalable size of particles of this chemical.
The inhalable coarse particles," have diameters larger than 2.5 micrometers and smaller than 10 micrometers and "fine particles," have diameters that are 2.5 micrometers and smaller.
Vapour pressure
Vapour pressure of piperazine compound with phosphoric acid is estimated to be 0.000000000436 mm Hg. This value is equivalent to 0.0000581 mPa. Thus, the chemical is expected to have low vapour pressure.
Partition coefficient
The experimental value of octanol water partition co-efficient (log Pow) of piperazine, compound with phosphoric acid by Shake flask method was found to be -0.5316 at temperature 37 deg C and pH of 6.16.This value indicates that piperazine, compound with phosphoric acid is hydrophilic in nature.
Water solubility
The experimental value of the water solubility of piperazine, compound with phosphoric acid was found to be 15400 mg/L at temperature of 37deg C indicating that piperazine, compound with phosphoric acid is very soluble in water.
Solubility in organic solvents / fat solubility
The experimental value of solubility of piperazine, compound with phosphoric acid in methanol at temperature of 37deg C was found to be 1500 mg/L. The equivalent value at 20oC is equal to 811 mg/L indicating that piperazine, compound with phosphoric acid is moderately soluble in methanol.
Surface tension
This end point was considered for waiver since the chemical piperazine, compound with phosphoric acid is a solid chemical. Under normal conditions, surface tension is an inherent property of liquids.
Flash point
The flash point for piperazine, compound with phosphoric acid was determined to be 230oC at 970 hPa atmospheric pressure. This value at 101 325 Pa is equivalent to 240.255 oC.
Auto flammability
Piperazine, compound with phosphoric acid did not catch fire on being exposed to air at room temperature of 37 deg C and atmospheric pressure of 970 hPa. This indicates piperazine, compound with phosphoric acid is not auto-flammable.
Flammability
From the experimental values of flammability, piperazine, compound with phosphoric acid ignited when the flame of Bunsen burner having temperature of 950 deg C was brought in contact with it. Thus it can be concluded that piperazine, compound with phosphoric acid is flammable only at high temperature of about 950 deg C. However since such high temperatures are not found under normal circumstances of transportation and use, piperazine, compound with phosphoric acid was considered non-flammable for chemical safety assessment.
Explosiveness
There are no chemical groups associated with explosive properties in piperazine, compound with phosphoric acid. Thereofre, it can be concluded that the chemical shall not exhibit explosive properties. Thus, as per column 2 of Annex VII this end point was considered for waiver.
Oxidising properties
Piperazine, compound with phosphoric acid was found to be weakly oxidising since 94.90 ml of KMnO4 was required for getting the end point of the redox titration for 100 g of piperazine, compound with phosphoric acid. Thus, the chemical was considered as not oxidising.
Stability in organic solvents and identity of relevant degradation products
Piperazine, compound with phosphoric acid was found to be stable in organic solvent dichloro methane and no degradation products were formed after 24 hours as evident from the GC-MS chromatogram obtained at 0 hours and that obtained after 24 hours.
pH
1% by volume solution of piperazine, compound with phosphoric acid was found to exhibit a pH of 6.11 at 25deg C. Thus 1% by volume solution of piperazine, compound with phosphoric acid is relatively acidic in nature.
Dissociation constant
The experimental pKa value for piperazine, compound with phosphoric acid was found to be 0.000012296 (average pKa value) at 37deg C indicating that the chemical has dissociation properties. Considering the reaction to be exothermic, the dissociation constant value at 20oC is equivalent to the following value of 0.0000000664
Viscosity
This end point was considered for waiver since viscosity is an inherent property of a liquid that offers resistance to its flow and piperazine, compound with phosphoric acid is a solid substance and hence this testing was considered scientifically unjustified for piperazine, compound with phosphoric acid.
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