Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-970-9 | CAS number: 549-56-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
For testing the skin sensitisation of the quinine sulphate, five patients were tested with a standard patch test. All five patients reacted to a 2% solution of quinine sulphate and became sensitized after short exposure time. Also in the case report of Hardie, 1978 one patients was tested with a patch test. The patch test was strongly positive at 48 h to 1% aqueous solution of quinine sulphate. Quinine sulphate is obviously a contact allergen.
Migrated from Short description of key information:
Quinine sulphate is a potent contact sensitizer.
Justification for selection of skin sensitisation endpoint:
Endpoint selection: 7.10.4
Skin sensitisation was shown in a human case report.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Quinine sulphate is obviously a contact allergen. Based on the results quinine bisulphate has to be classified category 1A.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
