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EC number: 208-031-3 | CAS number: 506-30-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The lethal concentration (LC50) value of Eicosanoic acid in fish [Carassius auratus] in a 96 hr study on the basis of mortality effect was estimated to be 4.67 mg/L. Based on this LC50 value,the substance may qualify for the aquatic classification.But after compairing with other CLP criteria for BCF and biodegradation it is concluded that Eicosanoic acid does not exhibit short term toxicity to fish (Carassius auratus) i.e. it is non hazardous to the aquatic environment.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 4.67 mg/L
Additional information
Based on weight of evidence approach the no.of studies were reviewed for short-term toxicity to fish from reliable sources having Klimish rating 2 and 4.
The summary of the results are presented below
Sr. No |
Endpoint |
Value |
Duration |
Basis of effect |
Species |
Sources |
1. |
LC50 |
4.67 mg/L |
96 hr. |
Mortality |
Carassius auratus |
Predicted data from QSAR for CAS : 506-30-9 |
2. |
LC50 |
12 mg/L |
96 hr. |
Mortality |
Oncorhynchus kisutch |
Experimental data for RA CAS : 57-11-4 |
3. |
LC50 |
>5 mg/L |
96 hr. |
Mortality |
Oryzias latipes |
Experimental data from study report for RA CAS : 112-85-6 |
4. |
LC50 |
40 mg/L |
48 hr |
Mortality |
Oryzias latipes |
Experimental data for RA CAS : 8002-13-9 |
Based on the studies summarized in the above table for the target substance Eicosanoic acid and the read across substance,the endpoint value was found to vary between lethal concentration (LC50) = 4.67 mg/L to 40 mg/L in a 48 hrs. to 96 hrs.study on the basis of mortality effect. Based on the LC50 values, the substance may qualify for the aquatic classification.But after compairing with other CLP criteria for BCF and biodegradation it is concluded that Eicosanoic acid does not exhibit short term toxicity to fish (Carassius auratus, Oncorhynchus kisutch and Oryzias latipes) i.e. it is non hazardous to the aquatic environment.
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