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EC number: 941-992-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Acute data
Several studies on BPS have been performed, and the fish LC50 values reported are higher than 100 mg/L. Therefore, it is non-toxic to fish.1 2 3
Acute invertebrate studies are also available on BPS and the LC50 results are higher than 45 mg/L. It is therefore, non-toxic for aquatic invertebrates.1 2 3 4
Acute algae studies reported an LC50 higher than 1 mg/L.1 2 3
The EC50 on STP, according to OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test) value was determined to be 390 mg/L.1 2 3
Therefore, there is no concern regarding the acute environmental exposure to fish, invertebrates and algae for BPS.
2,4'-sulfonyldiphenol CAS 5397-34-2 is considered non toxic for the aquatic compartment (C&L ECHA Inventory), and no data are available.
For a phenol sulfonic acid sodium salt, the benzenesulfonic acid, 4-hydroxy-, sodium salt (1:1), CAS 825-90-1, no measured data are available. Calculation of the relevant endpoints with the ECOSAR model predicts that hydroxybenzenesulphonic acid is not toxic to aquatic species. More realistic data on salified similar substances called hydrotropes, can be considered.
A category approach evaluation is available for sodium xylenesulphonate. The estimated ecotoxicological property of this substance can be helpful (in read across as well) to understand the acute ecotoxicity of sodium sulphonated phenols, part of the intermediate DCB.The sodium xylenesulphonate is considered non toxic for the acute exposure in the environmental compartment, STP included.5
Phenol is considered non toxic for the acute exposure in the environmental compartment.6
Chronic data
Long term Estimation on BPS according to ECOSAR (as phenols, poly) revealed no concern for fish, crustaceans and algae.1 2 3
Test on chronic exposure to crustaceans are available. The measured EC50 value on BPS for Daphnid was 14 mg/L while the measured NOEC was 2.7mg/L.1 2 3
Using a conservative approach, the unidentified LOEC for chronic toxicity in Daphnid is assumed to be between 2.7 and 14 mg/L, which partly spans the range of values that indicate a moderate hazard concern (1-10 mg/L).1 2 3
2,4'-sulfonyldiphenol CAS 5397 -34 -2 is considered non toxic for the aquatic compartment (C&L ECHA Inventory), and no data is available.
For phenol sulfonic acid sodium salt,benzenesulfonic acid, 4-hydroxy-, sodium salt (1:1), CAS 825-90 -1, no measured data is available .5
No data on long term exposure to the salified similar substances called hydrotropes, are available.
In the REACH Registration dossier of phenol, a chronic classification for the aquatic compartment has been proposed as self-classification, compared to the Annex VI harmonized classification. The substance is self-classified as an environmental toxicant (category 2, H411).6
References:
1ECHA Registration Dossier BPS CAS 80-09-1;
2SIDS INITIAL ASSESSMENT PROFILE, CAS 80-09-1, CoCAM 4, 16-18 April 2013;
3EPA, U.S. Environmental Protection Agency, Bisphenol A alternatives in thermal paper, Final Report, January 2014.
4Min-Yu Chen, Michihiko Ike and Masanori Fujita, Acute toxicity, mutagenicity, and estrogenicity of bisphenol-A and other bisphenols. Environmental Toxicology Volume 17, Issue 1, pages 80–86, 2002;
5HPV Assessment Report On Hydroxybenzenesulphonic acid CAS No. 1333-39-7, 2004, NOTOX.
6ECHA Registration Dossier Phenol CAS 108-95-2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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