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REACH

1,3,5-triazine-2,4,6(1H,3H,5H)-trione, trisodium salt

EC number: 221-255-6 | CAS number: 3047-33-4

Life Cycle description
Uses advised against

Toxicological information

Endpoint summary

Administrative data

Description of key information

Read-across from in vivo studies of skin and eye irritation (where cyanuric acid was non-irritating);so the same results can be extrapolated to trisodium cyanurate.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion

Endpoint conclusion:: no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion

Endpoint conclusion:: no adverse effect observed (not irritating)

Additional information

Read-across:

1. Based on the experimental results obtained with the analogue cyanuric acid (72h-primary dermal irritation index (PDII)= 0) , the read-across approach is applied and the 72h-primary dermal irritation index (PDII) for substance trisodium cyanurate is calculated to be 0 (skin irritation).

2. Based on the experimental results obtained with the analogue cyanuric acid (72h-overall irritation score= 0.3) , the read-across approach is applied and the same result can be extrapolated for substance trisodium cyanurate (eye irritation).

Justification for classification or non-classification

In the in vivo skin and eye irritation studies cyanuric acid was non-irritant and therefore requires no classification under DSD or CLP

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