Registration Dossier
Registration Dossier
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EC number: 256-435-3 | CAS number: 49701-24-8
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: well performed OECD study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- not specified
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- 4-amino-2,5-dimethoxy-N-methylbenzenesulphonamide
- EC Number:
- 256-435-3
- EC Name:
- 4-amino-2,5-dimethoxy-N-methylbenzenesulphonamide
- Cas Number:
- 49701-24-8
- Molecular formula:
- C9H14N2O4S
- IUPAC Name:
- 4-amino-2,5-dimethoxy-N-methylbenzene-1-sulfonamide
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 55 mg/L
- Temp.:
- 20 °C
- pH:
- ca. 4.5
- Details on results:
- HPLC conditions:
Column : Synergi Hydro RP, 250 mm x 4,6 mm ID, 4 μm
Eluent A : acetonitrile/phosphoric acid 0,05 mol/l = 5/95
Eluent B : acetonitrile/ phosphoric acid 0,05 mol/l = 95/5
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of the substance is 55 mg/L at 20°C. - Executive summary:
The water solubility of the substance was determined according to OECD guideline 105 with the flask method using HPLC for the analytics. The water solubility was found to be 55 mg/L at 20°C.
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