Registration Dossier
Registration Dossier
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EC number: 482-410-3 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Testing was not carried out according to Method C7 of Commission Directive 92/69/EEC and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004 as it was considered scientifically unjustified.HYDROWIN v1.67 (EPA 2000) was then used to estimate the half life of the material as it was predicted that the components with longer alkyl chains were generally more stable (longer half-life) than those with shorter alkly chains.
Key value for chemical safety assessment
Additional information
Testing was not carried out according to Method C7 of Commission Directive 92/69/EEC and Method 111 of the OECD Guidelines for Testing of Chemicals, 13 April 2004 for the following reasons:
· The test material is a complex mixture and the hydrolysis guidelines are not suitable for assessment mixtures.
· The test material has a very low water solubility value (<1.86 x 10-2mg/l). As the hydrolysis guidelines require an initial solution concentration of less than half the water solubility, the test concentration would be even lower.
· Even though a sensitive analytical method using GC-MS was developed and the test material extracted from water for the water solubility test to increase the limit of detection, negligible test material was observed on analysis. The limit value was calculated from predominant matrix peaks and baseline noise over the elution time period of the test material.
· Potentially, due to such a large number of peaks in the chromatography any hydrolysed larger test material components could co-elute at the same time as smaller components. This would then interfere with quantification of the test material parent molecules.
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