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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 482-480-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 September 2006 to 28 March 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- Only a preliminary test was performed.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- Only a preliminary test was performed.
- Principles of method if other than guideline:
- Only a preliminary test was performed. The main test could not be performed as it was virtually impossible to separate the test item from the aqueous phase on trying to prepare saturated solutions of test material in water.
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- < 10.9 other: micro g/mL
- Conc. based on:
- test mat.
- Remarks on result:
- other: Based on preliminary test.
- Remarks:
- Results at room temperature.
- Details on results:
- After mixing 54.72 mg of test material with 1 mL of water and adding stepwise up to 5 L of water, the test material remained undissolved.
A main test using the flask shaking method was not conducted as it was impossible to separate the test material from the aqueous phase on preparing saturated solutions of test material. - Conclusions:
- The water solubility of the test material, using visual inspection in a preliminary test, is estimated to be <10.9 micro g/mL at room temperature.
- Executive summary:
The water solubility of the test material, using visual inspection in a preliminary test, is estimated to be <10.9 micro g/mL at room temperature.
A main test could not be performed as it was virtually impossible to separate the test item from the aqueous phase on trying to preare saturated solutions of the test material in water.
Reference
The test material has a number of components, which have different solubilities, making it impossible to determine solubilities with a single analytical method. From a scientific viewpoint, however, visual determination, as performed in the preliminary test, is considered an acceptable way of determining the solubility of the test material in water.
Description of key information
The water solubility of the test material, using visual nspection in a preliminary test, is estimated to be <10.9 micro g/mL at room temperature.
Key value for chemical safety assessment
Additional information
A main test could not be performed as it was virtually impossible to separate the test item from the aqueous phase on trying to prepare saturated solutions of the test material in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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