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EC number: 424-970-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 and 21 June 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Version / remarks:
- 1984
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Storage temperature: room temperature
- Analytical monitoring:
- no
- Vehicle:
- yes
- Remarks:
- Tertiary butyl alcohol (used for the three lowest concentrations only)
- Details on test solutions:
- Control mixtures of 16 mL synthetic sewage feed and 284 mL dilution water were prepared in one liter glass beakers. An additional control was added containing 0.1 mL vehicle.
A series of 16 mL synthetic sewage feed, 284 mL dilution water, appropriate amounts of the test substance or its stock solution brought to 284 mL with dilution water were prepared in 1 liter beakers. The final nominal test concentrations were 0, 3.2, 10, 32, 100, 321 and 1000 mg/L.
Tertiary butyl alcohol was used for the three lowest concentrations; for the three highest concentrations the test item was added directly to the test mixture. - Test organisms (species):
- activated sludge of a predominantly domestic sewage
- Details on inoculum:
- Source sludge: oxidation ditch situated in the district of Hazerswoude Dorp, The Netherlands (domestic sewage treatment).
Sludge was centrifuged and washed twice in tap water and once in dilution water. The mixed liquor suspended solids content was found to be 7.1 g/L. The suspension was aerated vigorously and kept at approximately 20ºC. Fifty mL of synthetic sewage feed was added daily per liter of sludge suspension. The dry weight was checked prior to use in the test and a mixed liquor suspended solids level of 4.2 g/L was found. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
- Test temperature:
- 20ºC
- pH:
- 7.6
- Details on test conditions:
- The suspensions were aerated vigorously and incubated at approximately 20ºC for three hours. After three hours, a sample of each mixture was poured into a BOD (Biochemical Oxygen Demand) bottle (volume about 295 mL) and stirred vigorously on a magnetic stirrer. An oxygen electrode was inserted into the sample and the oxygen concentration was recorded every minute during a period of about 10 minutes.
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorophenol at 5, 12 and 30 mg/L
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Duration:
- 3 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Details on results:
- The results are included below.
No dose response relation was found for the respiration inhibition within the nominal concentration range of 3.2 to 1000 mg/L. The respiration rate within this range was on average 0.2% below the average of the initial and final control. - Results with reference substance (positive control):
- The EC50 of 3,5-dichlorophenol was found to be 5.02 mg/L (within the acceptable range of the OECD guideline).
The respiration rates of the initial and final controls were found to be 15.21 and 17.37 mg O2/g/h, respectively. The difference between the two values amounted to 13.3% being within the validity criterion (15%) of the OECD guideline. - Validity criteria fulfilled:
- yes
- Conclusions:
- SDBR was found not to inhibit microbial activity (NOEC = 1000 mg/L, based on nominal values).
Reference
Description of key information
SDBR was found not to inhibit microbial activity (NOEC = 1000 mg/L, based on nominal values).
Key value for chemical safety assessment
Additional information
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