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EC number: 500-046-6 | CAS number: 26183-52-8 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key information for the assessment of decan-1 -ol, ethoxylated, 1 -2.5 moles EO, CAS 26183 -52 -8
Acute toxicity based on read across study data
Fish: LC50 (96h) = 1.2 mg/L
Crustacea: EC50 (48h) = 0.39 mg/L
Algae: ErC50 (72h) = 0.43 mg/L
Chronic toxicity based on alcohol ethoxylate specific QSARs
Fish: EC20 (30d) >= 2.92 - <= 5.14 mg/L
Crustacea: EC20 (21d) >= 3.72 - <= 6.55 mg/L
Algae: ErC20 (72h) >=3.23 - <= 5.67 mg/L
Additional information
Category information on the aquatic hazard assessment of alcohol ethoxylate
The toxicity mechanism for alcohol ethoxylates is accepted to be non-polar narcosis (Boeije et al. 2006), in which the AE homologues with longer hydrocarbon chains and higher logKow are more efficient at penetration of the cell membrane, and thus more toxic. However, the alcohol ethoxylates homologues must be sufficiently soluble in water to allow a toxic concentration to reach the target organism. For the long chain alcohols (hydrocarbon chain lengths of 15 and above) the toxicity is restricted by solubility considerations. The available toxicity data follows this generally accepted pattern, and also indicates that the linear, essentially linear and branches AE are of similar toxicity (HERA, 2009).
Since long-term data are not available for all category members, precise long-term effect values were calculated with alcohol ethoxylate specific QSARs (Wind & Belanger, 2006; Boeije et al., 2006; Belanger et al., 2006). The used QSARs allow describing the toxicity for each registered mixture based on their individual composition. The effects are described as EC20 values, since the QSARs are more robust for the EC20 values than for NOEC or EC10 values (Boeije et al., 2006). As usual the lowest long-term value is used as key value for classification and labelling.
More details on the category approach are given in a separate document (see attached in IUCLID chapter 13).
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