4-hydroxybenzophenone

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

30 November 2018 to 27 May 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

March 04, 2016

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point/Boiling Range)

Version / remarks:

July 27, 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Version / remarks:

August 1996

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

Appearance: White powder
Purity/Composition: 99.72%
Test item storage: At room temperature desiccated

Key result

Atm. press.:

760 mm Hg

Decomposition:

yes

Decomp. temp.:

>= 300 °C

Preliminary Test

The TGA curve of the test item is shown in Figure 1.  Starting at 300°C, the weight of the sample decreased significantly.  At 367°C, the sample weight had decreased by 25%.

After the experiment, a brown molten residue remained in the sample container (original colour: white).  The change of the colour indicated reaction and/or decomposition of the test item.

Main Study

The DSC curve obtained with Experiment 1 is shown in Figure 2.  An endothermic effect was observed between 125°C and 150°C followed by an endothermic effect starting at 300°C.  The extrapolated onset temperature of the first effect was 133.349°C.  The endothermic effect was most likely obtained due to melting of the test item.  The second endothermic effect was probably obtained due to reaction and/or decomposition of the test item.

After the experiment, an orange molten residue remained in the sample container (original colour: white).  The change of the colour indicated reaction and/or decomposition of the test item.  Based on this visual observation, it was found that the test item had molten and the change of the colour demonstrated reaction and/or decomposition of the test item.

In order to investigate the endothermic effect, Experiment 2 was stopped directly after the melting effect.  Figure 3 shows the DSC curve obtained. The extrapolated onset temperature was 133.288°C.  After the experiment, a white molten residue remained in the sample container (original colour: white). It demonstrated that melting was the reason for the endothermic effect.

Conclusions:

The boiling temperature of 4-Hydroxy-benzophenone was determined by DSC.

Reaction and/or decomposition of the test item was observed during DSC experiment starting at 300°C (573K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Executive summary:

In this guideline (OECD 103) study conducted with GLP certification, the test material (EC 214-507-1) was determined to not have a boiling point as it starts to decompose at 300 °C.

Description of key information

Study conducted to recognised testing guidelines with GLP certification.

Additional information

Substance starts to decompose at 300 °C. Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started.  Based on this, the test item has no boiling temperature.