Registration Dossier
Registration Dossier
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EC number: 242-833-4 | CAS number: 19139-31-2
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ASTM D6355
- Deviations:
- not specified
- GLP compliance:
- no
Test material
- Reference substance name:
- Dihexyl fumarate
- EC Number:
- 242-833-4
- EC Name:
- Dihexyl fumarate
- Cas Number:
- 19139-31-2
- Molecular formula:
- C16H28O4
- IUPAC Name:
- dihexyl fumarate
Constituent 1
- Specific details on test material used for the study:
- 4% dilution in petrolatum
Test animals
- Species:
- other: Human
- Strain:
- not specified
Test system
- Type of coverage:
- occlusive
- Preparation of test site:
- not specified
- Vehicle:
- other: 4% in petrolatum
- Controls:
- not specified
- Duration of treatment / exposure:
- 48h
Results and discussion
In vivo
Resultsopen allclose all
- Remarks on result:
- no indication of irritation
- Irritation parameter:
- erythema score
- Time point:
- 24/48/72 h
- Remarks on result:
- not measured/tested
- Irritation parameter:
- edema score
- Time point:
- 24/48/72 h
- Remarks on result:
- not measured/tested
Any other information on results incl. tables
Tested at 4% in petrolatum. it produced no irritation after a 48-hr closed-patch test on human subjects
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- Tested at 4% in petrolatum. it produced no irritation after a 48-hr closed-patch test on human subjects
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