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EC number: 430-050-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The vapour pressure is estimated by calculation. The software (EPISuite MPBPVP (v1.43)) uses three different methods (Antoine method, modified grain method, Mackay method) to estimate the vapour pressure based on melting point and boiling point of the substance.
- GLP compliance:
- no
- Type of method:
- other: Calculation
- Specific details on test material used for the study:
- CAS Number: 123-26-2SMILES : CCCCCCC(CCCCCCCCCCC(=O)NCCNC(=O)CCCCCCCCCCC(CCCCCC)O)OCHEM : 12-hydroxy-N-[2-(12-hydroxyoctadecanoylamino)ethyl]octadecanamideMOL FOR: C38 H76 N2 O4MOL WT : 625.04
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Antoine Method
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Modified Grain Method
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Mackay Method
- Conclusions:
- The estimates for the vapour pressure of the test material are below 5E-17 Pa for all three methods used.
- Executive summary:
The vapour pressure of the test material is calculated from estimated melting and boiling point by MPBPVP, using EPI Suite. All three used models predict very low values for the vapour pressure at 25°C (< 5E-17 Pa). The EPA recommend that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
- Endpoint:
- vapour pressure
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The vapour pressure is estimated by calculation. The software (EPISuite MPBPVP (v1.43)) uses three different methods (Antoine method, modified grain method, Mackay method) to estimate the vapour pressure based on melting point and boiling point of the substance.
- GLP compliance:
- no
- Type of method:
- other: Calculation
- Specific details on test material used for the study:
- CAS Number: 146781-64-8SMILES : CCCCCCCCCC(=O)NCCNC(=O)CCCCCCCCCCC(CCCCCC)OCHEM : N-[2-(decanoylamino)ethyl]-12-hydroxyoctadecanamideMOL FOR: C30 H60 N2 O3MOL WT : 496.82
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Antoine Method
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Modified Grain Method
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Mackay Method
- Conclusions:
- The estimates for the vapour pressure of the test material are below 5E-13 Pa for all three methods used.
- Executive summary:
The vapour pressure of the test material is calculated from estimated melting and boiling point by MPBPVP, using EPI Suite. All three used models predict very low values for the vapour pressure at 25°C (< 5E-13 Pa). The EPA recommend that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
- Endpoint:
- vapour pressure
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The vapour pressure is estimated by calculation. The software (EPISuite MPBPVP (v1.43)) uses three different methods (Antoine method, modified grain method, Mackay method) to estimate the vapour pressure based on melting point and boiling point of the substance.
- GLP compliance:
- no
- Type of method:
- other: Calculation
- Specific details on test material used for the study:
- CAS Number: 51139-08-3SMILES : CCCCCCCCCC(=O)NCCNC(=O)CCCCCCCCCCHEM : N-[2-(decanoylamino)ethyl]decanamideMOL FOR: C22 H44 N2 O2MOL WT : 368.61
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Antoine Method
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Modified Grain Method
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Mackay Method
- Conclusions:
- The estimates for the vapour pressure of the test material are below 3.5E-9 Pa for all three methods used.
- Executive summary:
The vapour pressure of the test material is calculated from estimated melting and boiling point by MPBPVP, using EPI Suite. All three used models predict very low values for the vapour pressure at 25°C (< 3.5E-9 Pa). The EPA recommend that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EEC, A4 (Effusion method by loss of weight).
- GLP compliance:
- yes
- Type of method:
- effusion method: by loss of weight or by trapping vaporisate
- Temp.:
- 25 °C
- Vapour pressure:
- < 0 Pa
- Remarks on result:
- other: Estimated vapour pressure value.
Referenceopen allclose all
Vapor Pressure Estimations (25 deg C):
(Using BP: 801.18 deg C (estimated))
(Using MP: 349.84 deg C (estimated))
VP: 2.22E-040 mm Hg (Antoine Method)
: 2.96E-038 Pa (Antoine Method)
VP: 1.22E-024 mm Hg (Modified Grain Method)
: 1.62E-022 Pa (Modified Grain Method)
VP: 3.58E-019 mm Hg (Mackay Method)
: 4.78E-017 Pa (Mackay Method)
Vapor Pressure Estimations (25 deg C):
(Using BP: 675.64 deg C (estimated))
(Using MP: 294.64 deg C (estimated))
VP: 1.86E-026 mm Hg (Antoine Method)
: 2.48E-024 Pa (Antoine Method)
VP: 5.71E-019 mm Hg (Modified Grain Method)
: 7.61E-017 Pa (Modified Grain Method)
VP: 3.32E-015 mm Hg (Mackay Method)
: 4.43E-013 Pa (Mackay Method)
Vapor Pressure Estimations (25 deg C):
(Using BP: 550.10 deg C (estimated))
(Using MP: 236.00 deg C (estimated))
VP: 1.51E-014 mm Hg (Antoine Method)
: 2.01E-012 Pa (Antoine Method)
VP: 7.67E-012 mm Hg (Modified Grain Method)
: 1.02E-009 Pa (Modified Grain Method)
VP: 2.52E-011 mm Hg (Mackay Method)
: 3.36E-009 Pa (Mackay Method)
Description of key information
According to the study report, the vapour pressure of the substance is estimated ato be lower than 1E-5 Pa at 25 °C by using the Clausius–Clapeyron equation. A measurement by effusion method by loss of weight (92/69/EEC, A4) at 139.6 °C gave a result of 1E-6Pa, which could not be used to provide an estimation and confirm the calculated value.
In addition, the vapour pressure as calculated by MPBVP v1.43 is provided for each of the three components of the amide mixture. Therein, the highest vapour pressure at 25 °C was calculated for component N-[2-(decanoylamino)ethyl]decanamide (CAS 51139-08-3) as 3.36E-9 Pa (Mackay Method), which is less than the estimation by the study report.
Nevertheless, the EPA recommends that empirical measures should be preferentially considered. Since all estimated values are below 1E-5 Pa and experimental determination was not possible, the vapour pressure of the test material is regarded as negligible.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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