Registration Dossier
Registration Dossier
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EC number: 428-190-4 | CAS number: 68490-66-4 CUREZOL 2MA-OK
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 Sep 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Deviations:
- not specified
- GLP compliance:
- yes
- Remarks:
- Department of Health of the Government of the United Kingdom, Date of Inspection 12Apr2005
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficientopen allclose all
- Type:
- log Pow
- Partition coefficient:
- < 0.3
- Temp.:
- 30 °C
- pH:
- 4
- Type:
- log Pow
- Partition coefficient:
- < 0.3
- Temp.:
- 30 °C
- pH:
- 7
- Type:
- log Pow
- Partition coefficient:
- < 0.3
- Temp.:
- 30 °C
- pH:
- 10
- Details on results:
- At each pH value, the retention times of the two components of the test substance were shorter than that of 2-butanone, indicating a log Pow of less than 0.3. At pH 4, the components of the test substance co-eluted.
Any other information on results incl. tables
Conclusion
The test substance, 2MA-OK, was determined to have a log Pow of less than 0.3 at pH 4, 7 and 10.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
