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EC number: 295-371-0 | CAS number: 92044-91-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Remarks:
- Pseudomonas putida
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 Apr 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- DIN 38412-27 (Pseudomonas putida Zellvermehrungshemmtest)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: the required amount of test item was directly added to test vessel. - Test organisms (species):
- Pseudomonas putida
- Details on inoculum:
- - Laboratory culture: Pseudomonas putida, Migula, Berlin 33/2 (DSM 50026)
- Source: VTB microbiology, Henkel KGaA - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 min
- Test temperature:
- 21.0 - 21.1 °C
- Nominal and measured concentrations:
- Nominal: 30, 100, 300, 1000 and 10000 mg/L
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 100 mL Erlenmeyer flask
- Fill volume: 100 mL
- Aeration: yes
- No. of vessels per concentration (replicates): 2
- No. of vessels per control (replicates): 2
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: according to German standard DIN 38412, part 27, section 8.1 - Reference substance (positive control):
- not specified
- Duration:
- 30 min
- Dose descriptor:
- EC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Duration:
- 30 min
- Dose descriptor:
- EC10
- Effect conc.:
- 140 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Duration:
- 30 min
- Dose descriptor:
- EC50
- Effect conc.:
- 3 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Reported statistics and error estimates:
- Linear regression (Probit Analysis)
- Conclusions:
- The EC50 was 3200 mg/L for Pseudomonas putida.
Reference
Table 1: Inhibition of O2-consumption
Concentration [mg prod./L] |
Inhibition (mean value) [%] |
30 |
3.1 |
100 |
8.5 |
300 |
13.8 |
1000 |
34.4 |
10000 |
67.9 |
Description of key information
EC50 (30 min): 3200 mg/L for Pseudomonas putida (DIN 38412-27)
Key value for chemical safety assessment
Additional information
One study investigating the toxicity to microorganisms of Fatty acids, C8-10, oxybis(2-hydroxy-3,1-propanediyl) esters (CAS 92044-91-2) according to DIN 38412-27 is available. The test was conducted with Pseudomonas putida as test organisms. P. putida were exposed to nominal test concentrations of 30, 100, 300, 1000 and 10000 mg/Lfor 30 minutes. Based on the oxygen consubtion of the bacteria an EC50 (30 min) of 3200 mg/L (EC10 (30 min): 140 mg/L) based on nominal concentrations was determined.
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