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Diss Factsheets
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EC number: 948-047-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 Nov 1997 - 09 Jan 1998
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ISO 10708: Determination of biochemical oxygen demand in a two-phase closed bottle test
- Deviations:
- yes
- Remarks:
- temperature variations of > 0.5 °C
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Sewage from the wastewater treatment plant 'Hochdahl', Germany
- Laboratory culture: No
- Concentration of sludge: 1 mL sewage / inoculum - Duration of test (contact time):
- 56 d
- Initial conc.:
- 100 mg/L
- Based on:
- COD
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Test temperature: 18-22 °C
TEST SYSTEM
- Culturing apparatus: bottles with conical shoulder (approx. 296 mL volume)
- Number of culture flasks/concentration: 3
- Method used to create aerobic conditions: Stabilisation phase of one week (18-22 °C). Saturated with oxygen after stabilisation phase.
- Measuring equipment: WTW oxygen meter 'OXI 3000'
- Test performed in open system: no
SAMPLING
- Sampling frequency: Sampling was performed on day 0, 3, 7, 14, 21, 28, 56
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 3 replicates
- Abiotic sterile control: no
- Toxicity control: no
- Other: Positive control: sodium acetate, 3 replicates - Reference substance:
- acetic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 61
- St. dev.:
- 5
- Sampling time:
- 28 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 75
- St. dev.:
- 5
- Sampling time:
- 56 d
- Details on results:
- Day 3: 7%
Day 7: 22%
Day 14: 41%
Day 21: 53%
Day 28: 61%
Day 56: 75% - Results with reference substance:
- The reference substance meets the 10-day window and was degraded by 89% after 28 days and by 92% after 56 days, respectively.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- According to “OECD Guidelines for the testing of chemicals – Revised introduction to the OECD guidelines for testing of chemicals, Section 3 – Part 1: Principles and strategies related to the testing of degradation of organic chemicals degradation” published by OECD (2006) the ready biodegradability data for mixtures of structurally similar chemicalsshould be evaluated carefully. For substances with different chain lengths the 10-day window should not be used for the interpretation of results. It is possible that a sequential biodegradation took place which might have led to a prolonged lag-Phase and therefore a slower biodegradation period although the test substance was biodegraded in a large amount after the test duration. In this case the pass level can be applied at 28 days and is therefore readily biodegradable (61% after 28 days).
- Executive summary:
The chemical oxygen demand (COD) was defined using the Kelkenberg-method but there are indicators that is was not defined well (compared to the calculation of the theoretical oxygen demand (ThOD)). Anyway the COD was used for calculation.
According to “OECD Guidelines for the testing of chemicals – Revised introduction to the OECD guidelines for testing of chemicals, Section 3 – Part 1: Principles and strategies related to the testing of degradation of organic chemicals degradation” published by OECD (2006) the ready biodegradability data for mixturesof structurally similar chemicalsshould be evaluated carefully. For substances with different chain lengths the 10-day window should not be used for the interpretation of results. It is possible that a sequential biodegradation took place which might have led to a prolonged lag-Phase and therefore a slower biodegradation period although the test substance was biodegraded in a large amount after the test duration. In this case the pass level can be applied at 28 days and is therefore readily biodegradable (61% after 28 days).
Reference
The chemical oxygen demand (COD) was defined using the Kelkenberg-method but there are indicators that is was not defined well (compared to the calculation of the theoretical oxygen demand (ThOD)). Anyway the COD was used for calculation.
According to “OECD Guidelines for the testing of chemicals – Revised introduction to the OECD guidelines for testing of chemicals, Section 3 – Part 1: Principles and strategies related to the testing of degradation of organic chemicals degradation” published by OECD (2006) the ready biodegradability data for mixtures of structurally similar chemicals should be evaluated carefully. For substances with different chain lengths the 10-day window should not be used for the interpretation of results. It is possible that a sequential biodegradation took place which might have led to a prolonged lag-Phase and therefore a slower biodegradation period although the test substance was biodegraded in a large amount after the test duration. In this case the pass level can be applied at 28 days and is therefore readily biodegradable (61% after 28 days).
Description of key information
A reliable biodegradation screening study was available on the read across substance, Fatty acids, C16-18, esters with ethylene glycol / 91031-31-1 / 292-932-1. At days 28 and 56 the percentage biodegradation was 61 and 75%, fulfilling the 60% biodegradation criteria.
According to “OECD Guidelines for the testing of chemicals – Revised introduction to the OECD guidelines for testing of chemicals, Section 3 – Part 1: Principles and strategies related to the testing of degradation of organic chemicals degradation” published by OECD (2006) the ready biodegradability data for mixtures of structurally similar chemicals should be evaluated carefully. For substances with different chain lengths the 10-day window should not be used for the interpretation of results. It is possible that a sequential biodegradation took place which might have led to a prolonged lag-Phase and therefore a slower biodegradation period although the test substance was biodegraded in a large amount after the test duration. In this case the pass level can be applied at 28 days and is therefore readily biodegradable (61% after 28 days).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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