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Diss Factsheets
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EC number: 241-165-0 | CAS number: 17096-07-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
There are no reliable aquatic toxicity data available for 3-[3,3,3-trimethyl-1,1-bis[(trimethylsilyl)oxy]disiloxanyl]propyl methacrylate; CAS No. 17096-07-0, therefore a combination of QSAR prediction for the substance and good quality experimental data for structurally-related substances have been used to fulfil the data requirements for registration.
3-[3,3,3-Trimethyl-1,1-bis[(trimethylsilyl)oxy]disiloxanyl]propyl methacrylate undergoes hydrolysis in water (half-lives of 3.6 h at pH 4, 2.3 h at pH 5, 631 h at pH 7 and 5.3 h at pH 9 and 20-25°C are predicted by QSAR. The low solubility (5.8E-05 mg/L at 20°C (QSAR)) could limit the rate of the reaction at higher loadings in water. The hydrolysis products under dilute conditions in solution are 3-(trihydroxysilyl)propyl methacrylate and trimethylsilanol, Aquatic ecotoxicity data are available for 3-trimethoxysilylpropyl methacrylate (CAS No. 2530-85-0), which also undergoes hydrolysis in water to form the same silanol hydrolysis product as the registration substance. Aquatic ecotoxicity data are also available for trimethylsilanol (CAS No. 1066-40-6). These are included as read across data for completeness, although in view of the slow hydrolysis rate under neutral conditions, the chemical safety assessment for the environment focuses on the parent substance.
Reliable predicted short-term toxicity for invertebrates (Daphnia magna) and green algae are available. The relevant short-term values are:
Daphnia: EC50 (48 h): >limit of solubility in water
Algae: EC50 (72 h): >limit of solubility in water
In view of the physicochemical properties of the registration substance, the potential for long-term effects has also been considered qualitatively. Long-term aquatic effects would not be expected to be expressed below the limit of solubility, based on the very high value of log Kow.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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