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EC number: 242-554-8 | CAS number: 18748-98-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- no
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Key result
- Type:
- log Pow
- Partition coefficient:
- > 4.1
- Temp.:
- 23 °C
- pH:
- >= 6.3 - <= 6.6
Reference
A stock solution of the test substance in water saturated n-octanol was prepared. To 25 ml,
50 ml and 100 ml of the stock solution 50 ml of n-octanol saturated water were added. The
two-phase system was shaken vigorously at room temperature (23 °C) for one hour.
Subsequently the phases were separated by centrifugation for 20 min at 14500 rpm and the
test substance concentration in each phase was determined.
Stock solution : 1098 mg/l
Results in detail:
determ. no. stock solution [ml] water [ml] test substance conc. in water phase[mg/l] test substance conc. in noctanol phase [mg/l] log Pow
A1 25 50 < 0,05 612 > 4,1
A2 25 50 < 0,05 545 > 4,0
B1 50 50 < 0,05 586 > 4,1
B2 50 50 < 0,05 580 > 4,1
C1 100 50 < 0,05 504 > 4,0
C2 100 50 < 0,05 377 > (3,9)*
mean > 4,1
*: outlier, not evaluated
Recovery rate of test substance:
determ. no. test substance in stock solution [mg] test substance in n-octanol phase [mg] test substance in water phase [mg] sum [mg] recovery rate [%]
A1 27,5 15,3 < 0,0025 15,3 56
A2 27,5 13,6 < 0,0025 13,6 50
B1 54,9 29,3 < 0,0025 29,3 53
B2 54,9 29,0 < 0,0025 29,0 53
C1 109,8 50,4 < 0,0025 50,4 46
C2 109,8 37,7 < 0,0025 37,7 34
Remark:
During the shake flask test significant hydrolysis of the test substance occurred. Due to the
water content of the water-saturated n-octanol even in the n-octanol phase hydrolysis takes
place. The hydrolysis product n-octadecanol is present in the n-octanol phase. For estimation
of log Pow the remaining concentration of octadecyloxytrimethylsilane in the n-octanol phase
was evaluated.
Concentration of octadecanol (hydrolysis product) and octadecyloxytrimethylsilane in
n-octanol phases:
determ. no. octadecanol1) mg/l octadecyloxytrimethylsilane mg/l sum mg/l ratio octadecanol/octadecyloxytrimethylsilane recovery rate2) %
A1 376 612 988 38/62 90
A2 391 545 936 42/58 85
B1 266 586 852 32/68 78
B2 317 580 897 36/64 82
C1 428 504 932 46/54 85
C2 513 377 890 58/42 81
1) estimated with response factor of octadecyloxytrimethylsilane
2) sum of octadecanol and octadecyloxytrimethylsilane vs. applied amount of octadecyloxytrimethylsilane
Description of key information
log Pow: > 4.1
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.1
- at the temperature of:
- 23 °C
Additional information
The partition coefficient (log Pow) of the test substance was determined according to the
OECD Guideline for the Testing of Chemicals 107.
log Pow: > 4.1
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