Registration Dossier
Registration Dossier
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EC number: 239-343-8 | CAS number: 15306-17-9
Endpoint summary
Administrative data
Description of key information
LD50 oral rat > 2000 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Quality of whole database:
- Study conducted according to internationally accepted testing guidelines.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
An acute oral toxicity test on Tris(ethyl acetoacetato-O1',O3)aluminium according to OECD TG 423 Class method was performed and the result of this study was LD50 rat oral route > 2000 mg/kg bw .
According to the Commission Regulation (EU) 2016/863 of 31 May 2016 amending Annexes VII and VIII to Regulation (EC) No 1907/2006 testing by the dermal route does not need to be conducted if the substance does not meet the criteria for classification as acute toxicity or STOT SE by the oral route and no systemic effects have been observed in vivo studies with dermal exposure (e.g. skin irritation, skin sensitisation): LD50 rat oral route for Tris(ethyl acetoacetato-O1',O3)aluminium is major than 2000 mg/kg bw and no classification is required for acute oral toxicity. No dermal acute toxicity is expected and no new test is considered necessary because there is no exposure upon use. Classification as skin sensitiser requires higher protection for the workers.
Testing by inhalation route is not appropriate for Tris(ethyl acetoacetato-O1',O3)aluminium because the exposure of human via inhalation is unlike.
Justification for classification or non-classification
Tris(ethyl acetoacetato-O1',O3)aluminium is not classified for acute toxicity according to the CLP Regulation (EC.n.1272/2008). For justification see the results of available studies.
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