Tin sulphide

Sediment toxicity

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

sediment toxicity: short-term

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Justification for type of information:

Both substances contain the same ion (tin(II)) as active substance. Tin dichloride is significantly better water soluble when compared to tin sulfide. Further information is provided in the read across justification.

Reason / purpose for cross-reference:

read-across source

GLP compliance:

no

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

69.7 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

38.1 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Details on results:

LC50: 38.1 mg/L (95% C.I.: 30.5-41.7 mg /L)

Reported statistics and error estimates:

probit analysis

Validity criteria fulfilled:

not specified

Conclusions:

Tubifex tubifex 96h-LC50: 38.1 mg/L

Executive summary:

In an acute study, the acute toxicity of tin dichloride on Tubifex tubifex has been determined by Fargasova (1994). The test was performed similar to OECD 235. The result was based on dissolved tin ions. The 96-hour LC50 based on tin(II) is 30.0 mg/L.

 

Based on the molecular masses, the expected toxicity of tin sulfide was calculated to be 38.1 mg/L. This is more than a factor of 500000 above the limit of water solubility of tin sulfide. Hence it can be concluded that tin sulfide will have no acute toxic effects on Tubifex tubifex.

Reference 2

Endpoint:

sediment toxicity: short-term

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Justification for type of information:

Both substances contain the same ion (tin(II)) as active substance. Tin dichloride is significantly better water soluble when compared to tin sulfide. Further information is provided in te read across justification.

Reason / purpose for cross-reference:

read-across source

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

10.541 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

4.572 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Details on results:

In the source study, the toxicity with tin dichloride was reported as LC50: 3.6 mg Sn/L (95% C.I.: 3.0-4.2 mg Sn /L)

Molecular mass:
Sn: 118,710 g/mol (rounded)
S: 32,06 g/mol (rounded)
molecular mass of tin sulfide; 150.775 g/mol

The hypothetical toxicity of tin sulfide was calculated as
LC50 (based on Sn(II) )*molecular mass of tin sulfide / molecular mass of tin=LC50 (based on tin(II))*1.27

Example:
The LC50 for tin(II) is 3.6 mg/L. This corresponds to 4.572 mg/L tin sulfide.

Reported statistics and error estimates:

probit analysis

Validity criteria fulfilled:

not specified

Conclusions:

Chironomus plumosus 96h-LC50: 4.572 mg/L

Executive summary:

In an acute study, the acute toxicity of tin dichloride on Chironomus plumosus has been determined by Fargasova (1994). The test was performed similar to OECD 235. The result was based on dissolved tin ions. The 96-hour LC50 based on tin(II) is 3.6 mg/L.

 

Based on the molecular masses, the expected toxicity of tin sulfide was calculated to be 4.572 mg/L.

This is more than a factor of 5000 above the limit of water solubility of tin sulfide. Hence it can be concluded that tin sulfide will have no acute toxic effects on Chironomus plumosus.

Description of key information

In an acute study, the acute toxicity of tin dichloride on Chironomus plumosus has been determined by Fargasova (1994). The test was performed similar to OECD 235. The result was based on dissolved tin ions. The 96-hour LC50 based on tin(II) is 3.6 mg/L. Based on the molecular masses, the expected toxicity of tin sulfide was calculated to be 4.572 mg/L. This is more than a factor of 5000 above the limit of water solubility of tin sulfide. Hence it can be concluded that tin sulfide will have no acute effects on Chironomus plumosus.

 

In an acute study, the acute toxicity of tin dichloride on Tubifex tubifex has been determined by Fargasova (1994). The test was performed similar to OECD 235. The result was based on dissolved tin ions. The 96-hour LC50 based on tin(II) is 30.0 mg/L. Based on the molecular masses, the expected toxicity of tin sulfide was calculated to be 38.1 mg/L. This is more than a factor of 500000 above the limit of water solubility of tin sulfide. Hence it can be concluded that tin sulfide will have no acute toxic effects on Tubifex tubifex.